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RNA-aptamer-mediated Bacteriophage Purification

A more productive, less expensive method for purifying nanoscale biological entities such as bacteriophages, viruses, virus-like particles (VLPs), and ribosomes. Background: Working with nanometer-sized biological entities, such as viruses, virus-derivatives, and super-molecular assemblies, typically requires a purification step. Currently, this...

Published: 5/13/2025 | Inventor(s): Ing-Nang Wang, Hua Shi, Jia Sheng, Alan Chen

Keywords(s): bacteriophage purification, phage purification, phage therapy, RNA aptamer, Technologies

Category(s): Campus > University at Albany, Technology Classifications > Biological Materials, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Healthcare, Technology Classifications > Research Tools and Reagents, Technology Classifications > Therapeutics and Vaccines

LORI: Local Low-Rank Imputation for Context-Aware AI

THE CHALLENGE Leveraging Artificial Intelligence (AI) for data-driven decision-making faces a major challenge in automatically configuring and optimizing complex AI pipelines across different use cases. As organizations deal with diverse datasets and fast-changing requirements, selecting the right combination of processing steps becomes increasingly...

Published: 4/16/2025 | Inventor(s): Ran Jin, Chen Xiaoyu

Keywords(s):

Category(s): Technology Classifications > Software

Attention-on-Attention for Human-Guided AI

THE CHALLENGE A major challenge facing industries like advanced manufacturing and quality inspection is the gap between human expertise in visual search and the limited capabilities of current AI systems. While skilled inspectors can dynamically scan, interpret, and integrate subtle visual cues over time, most existing automated solutions rely on static...

Published: 4/16/2025 | Inventor(s): Ran Jin, Chen Xiaoyu

Keywords(s):

Category(s): Technology Classifications > Communication, Technology Classifications > Software

Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay

Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...

Published: 5/30/2025 | Inventor(s): Yong Zeng, He Yan

Keywords(s):

Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics

Anti-Thrombin Nanoparticles and Therapeutics to Treat Necrotizing Enterocolitis

Advantages: Bivalirudin-tagged nanoparticles bind and neutralize nascent thrombin in clots, minimizing systemic anticoagulant effects Anti-thrombin nanoparticle confines its anticoagulant activity to sites of clot formation, limiting excessive systemic coagulation inhibition Dual therapeutic and diagnostic potential allows clinicians to treat NEC...

Published: 2/5/2025 | Inventor(s): Akhil Maheshwari, Samuel Wickline, Koppenruncholan Namachivayam, Hua Pan

Keywords(s): Gastrointestinal / Digestive Health, Pharmaceuticals

Category(s): Technology Classifications > Medical > Pharmaceuticals

Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations

The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...