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Search Results - hongyu+qiu
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Novel Therapy for Ischemic and Pressure-Overload Heart Diseases
This novel therapy involves using valosin-containing protein (VCP) to prevent or treat ischemic and pressure overload-induced heart disease. Inactivation and reduced VCP expression are highly associated with multiple cardiac diseases. Overexpression of VCP in the heart has been found to reduce infarct size during ischemia-reperfusion injury and also...
Published: 12/12/2025
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Inventor(s):
Hongyu Qiu
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Heart and Vascular
,
Technology Classifications > Life Sciences > Biologics
,
Technology Classifications > Life Sciences > Therapeutics
Novel Mechanism-Based Therapy for Aortic Stiffening and Related Cardiovascular and Cerebrovascular Disorders
This invention involves a novel mechanism-based therapy by using a small molecule compound to reduce aging and hypertensive aortic stiffening, subsequently improve blood pressure (BP) control in resistant hypertension patients and prevent or reverse pathologies of vascular cognitive impairment and dementia (VCID) and Alzheimer’s Disease (AD)....
Published: 11/24/2025
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Inventor(s):
Hongyu Qiu
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Heart and Vascular
,
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Life Sciences > Small Molecules
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Technology Classifications > Life Sciences > Therapeutics
Repurposing the FDA-Approved Antibody to Treat Aortic Stiffening and Resistant Hypertension
This innovation repurposes an FDA-approved antibody to treat and prevent aortic stiffening and resistant hypertension (RH). This mechanism-based therapeutic, inhibits receptor mediated inflammatory and pro-stiffness signaling to reduce aortic stiffness and improve blood pressure control, ultimately breaking the root cycle of hypertension. Background:...
Published: 11/24/2025
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Inventor(s):
Hongyu Qiu
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Heart and Vascular
,
Technology Classifications > Life Sciences > Biologics
,
Technology Classifications > Life Sciences > Therapeutics
Pioneering Cell-Based Solutions for Vascular Aging
This invention is a mechanism-based cell therapy for treating aortic stiffening, particularly in cases of old hypertension patients that do not respond to current treatments. It is also intended to help prevent cardiovascular disease and promote healthy aging in older populations. Background: Aortic stiffening is a critical age-related risk factor...
Published: 9/15/2025
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Inventor(s):
Hongyu Qiu
,
Liwu Li
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Heart and Vascular
,
Technology Classifications > Life Sciences > Therapeutics
New Microfabrication Technology for Producing Sensing Cells for MET Based Seismometer
Molecular Electric Transducer (MET) seismometer cells detect motion based on the movement of liquid electrolyte between electrodes. A MET sensing element consists of electrodes with spacers that are suspended across a narrow channel containing a liquid electrolyte. Holes through the electrodes allow electrolytes to flow along the length of the channel....
Published: 2/13/2025
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Inventor(s):
Hongyu Yu
,
Hai Huang
Keywords(s):
Materials and Electronics
,
Mechanical and Manufacturing
Category(s):
Advanced Materials/Nanotechnology
Tilt sensors based Molecular Electronic Transducers
An inclinometer is a gravity sensitive device which is capable of measuring angles of tilt. These tilt sensors have a broad range of applications, from seismology and aviation to consumer electronics. The variety and scope of these applications means that inclinometers must have high resolution and accuracy, while also providing reliable performance...
Published: 2/13/2025
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Inventor(s):
Hongyu Yu
,
Mengbing Liang
Keywords(s):
Materials and Electronics
,
Mechanical and Manufacturing
Category(s):
Advanced Materials/Nanotechnology
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Chemical/Biological Sensors
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Physical Science
ComprehENotes: Assessing patients' comprehension of their medical conditions and treatment
Many medical patients are now able to directly access their electronic health records (EHR). Providing such direct access has been shown to lead to improved healthcare outcomes through the patient’s enhanced understanding of their medical conditions and treatment. However, EHR contain medical jargon that challenge populations with lower health...
Published: 6/26/2023
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Inventor(s):
John Lalor
,
Hao Wu
,
Li Chen
,
Kathleen Mazor
,
Hong Yu
Keywords(s):
Category(s):
Healthcare
,
Research tools
MET Based Accelerometer Using Ethylammonium Nitrate (EAN) Based Potassium Iodide Droplets as the Sensing Body
Molecular Electronic Transducer (MET) seismometer cells are inertial sensors which detect motion based on the movement of liquid electrolyte between electrodes. A MET sensing element consists of electrodes with spacers that are suspended across a narrow channel containing a liquid electrolyte. Holes through the electrodes allow electrolytes to flow...
Published: 2/23/2023
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Inventor(s):
Lenore Dai
,
Hongyu Yu
,
Miranda Ngan
,
Mengbing Liang
,
Hai Huang
,
Denzil Frost
,
Stella Nickerson
Keywords(s):
Materials and Electronics
,
Mechanical and Manufacturing
Category(s):
Applied Technologies
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Bioanalytical Assays, Chemistries & Devices
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Chemical/Biological Sensors
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Physical Science
,
Physics
Film Bulk Acoustic Resonator Based Radiation Sensors
Ionizing radiation sensing has many applications in a variety of industries. Low dose sensing is important for nuclear materials detection and security. Some space applications require measurement of the flux and direction of high energy radiation. Furthermore, it is essential to determine the exact location and amount of radiation directed...
Published: 2/23/2023
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Inventor(s):
Hongyu Yu
,
Jonathon Oiler
,
Hugh Barnaby
Keywords(s):
Category(s):
Physical Science
,
Medical Diagnostics/Sensors
Film Bulk Acoustic-Wave Resonator Based Ethanol Sensor
Breath alcohol analyzers have been used as a quick and reliable testing device at sobriety checkpoints for individuals suspected of driving under the influence of alcohol. Acetone is typically considered the only endogenous volatile organic compound that can potentially prevent an accurate reading from being produced. It is naturally in a person's...
Published: 2/23/2023
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Inventor(s):
Hongyu Yu
,
Xiaotun Qiu
Keywords(s):
Category(s):
Physical Science
,
Medical Diagnostics/Sensors
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