Pioneering Cell-Based Solutions for Vascular Aging

This invention is a mechanism-based cell therapy for treating aortic stiffening, particularly in cases of old hypertension patients that do not respond to current treatments. It is also intended to help prevent cardiovascular disease and promote healthy aging in older populations.

Background: 
Aortic stiffening is a critical age-related risk factor that worsens hypertension and drives cardiovascular and neurodegenerative disease, yet no therapies directly target it, creating a major barrier to managing hypertension in older patients, leading to severe complications and premature mortality. Novel therapeutics that address the root cause could transform patient care by improving blood pressure control, reducing cardiovascular morbidity and mortality, and promoting healthier aging.

Applications: 

• Cell-based therapeutic
• Vascular therapeutic
• Regenerative medicine
• Personalized therapy

Advantages: 

• Potentially prevent cardiovascular disease
• Improve outcome of current therapy
• Promotes healthy aging in older populations
• Potentially less invasive than existing treatments