Search Results - michael+kuhns

3 Results Sort By:
AI-Assisted Computational Prediction of Protein Functionality
This invention centers on creating a database and algorithms to explore protein functionality and interactions. The aim is to enable significant scientific discoveries, novel drug targeting, and the engineering of synthetic receptors like chimeric antigen receptors (CARs). By studying proteins involved in T cell activation over 450 million years of...
Published: 4/17/2025   |   Inventor(s): Michael Kuhns, Koenraad Van Doorslaer, Kevin Scott, Andrew Girvin
Keywords(s):  
Category(s): Technology Classifications > Software & Information Technology > Health IT, Technology Classifications > Research Tools, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation
Alternative Translation Initiation and Termination of Immunoglobulin (Ig) Folds (AltIg) for the Synthesis of Bifunctional Polypeptides
This invention is a novel way to create Alternative Igs (AltIgs). This invention could be used to fuse two proteins together as a single polypeptide by fusing the AltIg end of one protein to the other protein. This would create a different spatial relationship between the proteins than could be achieved if the native Ig was fused in a conventional manner. Background: Fusing...
Published: 3/5/2025   |   Inventor(s): Michael Kuhns, Mark Lee, Deepta Bhattacharya
Keywords(s):  
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Immunology, Autoimmune & Inflammation, Technology Classifications > Healthcare Portfolios > Oncology
Tools And Techniques To Identify Antigen-Specific T Cells
This invention is a new tool and technique for identification of antigen-specific t cells. By using specific molecules from specified cell lines as antigen presenting cells, the identified T cells are labeled with different fluorescence. These cells go through the flow cytometry and the flow cytometry data is analyzed by a specific assay designed by...
Published: 11/1/2024   |   Inventor(s): Michael Kuhns, Bradley Moffett, Caleb Kim, Mark Lee
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Screening assays, Technology Classifications > Life Sciences