Search Results - hongjie+yuan

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Small Molecule Compound to Treat Neurological Diseases
Application NMDAR agents for the treatment of various neurological diseases. Key Benefits Exemplary compound EU1180-490 is a potent and selective potentiator of GluN1/GluN3 NMDARs. The compound has excellent Lipinski drug-like properties including low molecular weight and cLogP, as well as water solubility. The initial studies have determined...
Published: 7/30/2024   |   Inventor(s): Dennis Liotta, Stephen Traynelis, Hongjie Yuan, Matthew Epplin, Samantha Summer, David Menaldino, Leon Jacobs, Adam McCallum
Keywords(s): Neuroscience/Pain, Small Molecule
Category(s): TechPub Algolia > Drug Discovery, TechPub Algolia > Therapeutics
ComprehENotes: Assessing patients' comprehension of their medical conditions and treatment
Many medical patients are now able to directly access their electronic health records (EHR). Providing such direct access has been shown to lead to improved healthcare outcomes through the patient’s enhanced understanding of their medical conditions and treatment. However, EHR contain medical jargon that challenge populations with lower health...
Published: 6/26/2023   |   Inventor(s): John Lalor, Hao Wu, Li Chen, Kathleen Mazor, Hong Yu
Keywords(s):  
Category(s): Healthcare, Research tools
A System For Visual Presentation Of Concepts From Ontology And Text Documents
PAGE TITLEOverviewPAGE SUMMARYA system lets a user click on a location of a brain model to explore neuroscience ontology terms related to the location. The user can further explore the related terms and related documents through a visualization interface and learn new concept or document relationships derived from the ontology and annotated document...
Published: 7/24/2024   |   Inventor(s): Yuan An, Xia Lin, Mi Zhang, Yue Shang
Keywords(s):  
Category(s): Computing, Software, Analytics & Information Technology, Computing, Software, Analytics & Information Technology > Computing: Algorithms, Computing, Software, Analytics & Information Technology > Computing: Contextual Analytics, Computing, Software, Analytics & Information Technology > Computing: Data Mining, Computing, Software, Analytics & Information Technology > Computing: Databases
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 4/19/2023   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging