Search Results - heewook+lee

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Model for TCR Analysis and its Application to TCR-Epitope Binding Prediction and TCR Clustering
T cell receptors (TCRs) play an important role in the adaptive immune system. The ability to accurately predict or characterize binding interactions between TCRs and target antigens, partly because of the vast diversity of TCRs and epitopes, is challenging. While there has been progress in the development of computational models dedicated to this, the...
Published: 2/26/2026   |   Updated: 1/26/2024   |   Inventor(s): Heewook Lee, Pengfei Zhang, Michael Cai, Seojin Bang
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Vaccines/Antimicrobials
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit Endospores
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit EndosporesResearchers at Augusta University have invented skin-friendly compositions and methods for killing, inactivating, or otherwise reducing the bacterial endospores by using an effective amount of the green tea EGCG or its derivatives. EGCG research shows clear application for a hand sanitizer...
Published: 4/21/2023   |   Updated: 1/15/2021   |   Inventor(s): Stephen Hsu, Lee Lee, Tin-Chun Chu
Keywords(s):  
Category(s): Therapeutics
Microfluidic 3D Osteocyte Network Reconstructured With Microbeads As Scaffold
Background: Mature osteocytes embedded in the three-dimensional lacuna-canalicular network (3D-LCN) structure are known to sense local compressive strain and initiate strain-dependent new bone formation by osteoblasts, utilizing cytokines such as sclerostin and Dkk1 expressed by the osteocytes as major signaling molecules. Studying these osteocytes...
Published: 7/24/2026   |   Updated: 5/19/2015   |   Inventor(s): Woo Lee, Yexin Gu, Wenting Zhang, Qiaoling Sun, Jenny Zilberberg
Keywords(s):  
Category(s): Bio Technology (Rx, dev's, sys)
An Ex Vivo Human Multiple Myeloma Cancer Niche and Its Use As a Model for Personalized Treatment of Multiple Myeloma
Background:Primary patient-derived multiple myeloma cells (MMC) are difficult to preserve . Long-term survival of osteoblasts, OSB, is the most critical factor in maintaining the ex vivo viability and proliferative capacity of MMC. The adhesion and retention of MMC to the tissue scaffold was meditated by osteoblastic N-cadherin, as one of potential...
Published: 7/24/2026   |   Updated: 5/19/2015   |   Inventor(s): Woo Lee, Wenting Zhang, Peter Tolias, Hongjun Wang, Jenny Zilberberg, David Siegel
Keywords(s):  
Category(s): Bio Technology (Rx, dev's, sys)