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An Ex Vivo Human Multiple Myeloma Cancer Niche and Its Use As a Model for Personalized Treatment of Multiple Myeloma
Background:Primary patient-derived multiple myeloma cells (MMC) are difficult to preserve . Long-term survival of osteoblasts, OSB, is the most critical factor in maintaining the ex vivo viability and proliferative capacity of MMC. The adhesion and retention of MMC to the tissue scaffold was meditated by osteoblastic N-cadherin, as one of potential...
Published: 10/20/2025   |   Inventor(s): Woo Young Lee, Wenting Zhang, Peter Tolias, Hongjun Wang, Jenny Zilberberg, David Siegel
Keywords(s):  
Category(s): Bio Technology (Rx, dev's, sys)