Search Results - jenny+zilberberg

2 Results Sort By:
Microfluidic 3D Osteocyte Network Reconstructured With Microbeads As Scaffold
Background: Mature osteocytes embedded in the three-dimensional lacuna-canalicular network (3D-LCN) structure are known to sense local compressive strain and initiate strain-dependent new bone formation by osteoblasts, utilizing cytokines such as sclerostin and Dkk1 expressed by the osteocytes as major signaling molecules. Studying these osteocytes...
Published: 10/16/2025   |   Inventor(s): Woo Young Lee, Yexin Gu, Wenting Zhang, Qiaoling Sun, Jenny Zilberberg
Keywords(s):  
Category(s): Bio Technology (Rx, dev's, sys)
An Ex Vivo Human Multiple Myeloma Cancer Niche and Its Use As a Model for Personalized Treatment of Multiple Myeloma
Background:Primary patient-derived multiple myeloma cells (MMC) are difficult to preserve . Long-term survival of osteoblasts, OSB, is the most critical factor in maintaining the ex vivo viability and proliferative capacity of MMC. The adhesion and retention of MMC to the tissue scaffold was meditated by osteoblastic N-cadherin, as one of potential...
Published: 10/20/2025   |   Inventor(s): Woo Young Lee, Wenting Zhang, Peter Tolias, Hongjun Wang, Jenny Zilberberg, David Siegel
Keywords(s):  
Category(s): Bio Technology (Rx, dev's, sys)