Search Results - genetic+engineering

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Recombinant Enzyme for the Accurate Insertion of Novel DNA Sequences in Eukaryotic Cells
RPI ID: 2022-044-301 Innovation Summary: This gene editing system introduces a recombinant enzyme composed of an HIV integrase (HIV IN) tetramer and two or more Transcription Activator-Like Effectors (TALEs) bound via polypeptide linkers. The enzyme is designed to enable site-specific DNA insertion in eukaryotic cells with minimal off-target effects....
Published: 3/10/2026   |   Updated: 3/10/2026   |   Inventor(s): Mattheos Koffas, William Lawler
Keywords(s): Gene Integration, Genetic Engineering, Recombinant Proteins, Somatic Cell Editing
Category(s): Biotechnology and the Life Sciences
An Interactive Educational Aid
Reference #: 01505 The University of South Carolina is offering licensing opportunities for An Interactive Educational Aid Background: Teaching methods, tools and resources are the key to comprehensive understanding. However, most of the teaching/learning mode is textbook based that primarily delivers bookish knowledge and lacks the core fundamental...
Published: 3/16/2026   |   Updated: 6/10/2021   |   Inventor(s): Sujit Pujhari, Sanjeeta Paul
Keywords(s): DNA, educational device, genetic engineering, interactive tool, plasmid, recombinant DNA technology, RNA, science teaching aid
Category(s): Software and Computing, Chemistry and Biochemistry, Biomedical and Life Sciences, Research Tools
Targeting specific neurons for personalized next-gen therapeutics
Technology summary Neurological and cognitive disorders such as epilepsy, pain, fear and anxiety, depression, addiction, apnea and tremors can result from aberrant activity of defined subsets of neurons, including an imbalance of excitatory versus inhibitory signaling. However, it is difficult to alter neuron function selectively in the brain for research...
Published: 1/13/2026   |   Updated: 2/4/2021   |   Inventor(s): Boris Zemelman
Keywords(s): Genetic engineering, Neurodegenerative disease, Neurology, Neurosciences
Category(s): Life sciences > Therapeutics > Gene therapy