Search Results - boris+zemelman

2 Results Sort By:
Expression system for labeling and targeting cells with elevated calcium levels
The technology describes a system for labeling and targeting cells with elevated calcium levels, such as cancer cells or activated neurons, using a CREB reporter system. This system includes a synthetic CRE enhancer linked to promoters that control the expression of genes encoding functional proteins like reporters, ion channels, or therapeutic agents,...
Published: 9/16/2024   |   Inventor(s): Boris Zemelman
Keywords(s):  
Category(s): Life sciences > Research tools > Reagent, Life sciences > Therapeutics > Formulation
Targeting specific neurons for personalized next-gen therapeutics
Technology summary Neurological and cognitive disorders such as epilepsy, pain, fear and anxiety, depression, addiction, apnea and tremors can result from aberrant activity of defined subsets of neurons, including an imbalance of excitatory versus inhibitory signaling. However, it is difficult to alter neuron function selectively in the brain for research...
Published: 11/1/2023   |   Inventor(s): Boris Zemelman
Keywords(s): Genetic engineering, Neurodegenerative disease, Neurology, Neurosciences
Category(s): Life sciences > Therapeutics > Gene therapy