Search Results - facs

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Conformational Restriction of Cyanine Fluorophores in Far-Red and Near-IR Range
Abstract: Small molecule fluorescent probes are important tools in diagnostic medicine. Existing far-red and near-IR cyanine fluorophores (e.g. Cy5, Alexa 647, Cy7, ICG) are active in the far-red and near-range, but these agents suffer from modest quantum yields (brightness) which limit wide utility. It has been reported that the limited brightness...
Published: 4/8/2024   |   Inventor(s): Martin Schnermann, Megan Michie
Keywords(s): CANCER, Cardiovascular, cyanine fluorophores, FACS, Fluorescence guided surgery, Fluorescent probes, gastrointestinal (GI), IMAGING, KIDNEY, Schnermann, super resolution microscopy
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Collaboration Sought > Licensing, TherapeuticArea > Cardiology, Application > Diagnostics, TherapeuticArea > Gastroenterology, TherapeuticArea > Nephrology
RECONSTITUTION OF SPLIT-HALOTAG VIA ORTHOGONAL TAG BINDING DOMAINS
RECONSTITUTION OF SPLIT-HALOTAG VIA ORTHOGONAL TAG BINDING DOMAINS Researchers at UCSF have developed a method using split HaloTags to tag multiple proteins in a single assay and measure their interactions. Due to new technologies such as CRISPR/Cas9 gene editing, it is now easier to modify DNA than at any other point in human history. One of the...
Published: 5/18/2023   |   Inventor(s): David Brown, Suraj Makhija, Bo Huang
Keywords(s): FACS, HaloTag, Knock-In Cell Lines, Protein Fragment, Self-Complementing Protein Fragments, Split Protein System
Category(s): Technology Classifications > Biology