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Pharmaceutical manufacturing of the future: a continuous 3D printing approach for personalized medicine
Background Driven by personalized medicine, 3D printing has emerged as a promising technology for creating tailored pharma­ceutical dosage forms. One of its methods, Fused Deposition Modeling (FDM), is particularly notable for its ability to produce complex geometries using thermoplastic polymers. However, current FDM processes face significant...
Published: 1/8/2025   |   Inventor(s): Mohammed Maniruzzaman, Vineet Kulkarni, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Laser apparatus for micro-volume tissue excision
This technology uses a laser to remove tiny pieces of tissue for analysis. The laser is shaped into a ring and can be combined with cooling techniques to minimize damage. Background The traditional histopathology workflow, while considered the gold standard for tissue diagnosis, suffers from several limitations. These include the invasiveness of biopsies,...
Published: 1/8/2025   |   Inventor(s): Thomas Milner, James Tunnell, Jason King, Nitesh Katta
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Medical technology
Highly sensitive pressure sensor for diverse applications
A flexible, highly sensitive pressure sensor combines resistive and capacitive elements using a porous carbon nanotube–Eco flex material. It accurately detects a wide range of pressures, is easy to fabricate, and suits diverse applications like medical monitoring and environmental sensing. Background Pressure sensing technology plays a crucial...
Published: 1/8/2025   |   Inventor(s): Nanshu Lu, Kyoung-Ho Ha
Keywords(s):  
Category(s): Life sciences > Medical technology
Autonomous Brain Machine Interface
An advanced system that enables patients to better control prosthetic devices. Background: Many pathologies lead to loss of the ability to use one or more limbs. Historically, the lost or damaged limb is replaced with a prosthetic device. In recent years prosthetic technology has been developed to enable the control of these devices via a neural signal...
Published: 1/7/2025   |   Inventor(s): Joseph Francis, Venkata S. Aditya Tarigoppula, Brandi Marsh
Keywords(s):  
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Computers
Intramedullary Temporomandibular Joint (TMJ) Implant
A novel TMJ implant that reduces stress and strain on the patient. Background: The temporomandibular joint (TMJ) is involved in functions such as chewing, swallowing, and speaking. Degenerative disorders of the TMJ are typically treated with anti-inflammatory drugs. However, once the TMJ has been compromised, surgical treatment is commonly performed....
Published: 1/7/2025   |   Inventor(s): Martin Pendola
Keywords(s):  
Category(s): Campus > SUNY Downstate Health Sciences University, Technology Classifications > Medical Devices
Cancer treatment through hTERT inhibition
Title: Cancer Treatment Through hTERT Inhibition Invention: The invention is a small molecule that reduces human telomerase reverse transcriptase (hTERT), which is highly activated in cancer cells. Background: In 2010, approximately 73,599 U.S. patients were diagnosed with melanoma with 8,700 of those incidences resulting in death. A hallmark of cancer,...
Published: 1/7/2025   |   Inventor(s): Laurence Hurley, Vijay Gokhale, HyunJin Kang, Kui Wu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology
Chimetic Antigen Receptor (CAR)-Stem Cells (MSCs) and its use for Cardiovascular Diseases
This technology describes Chimetic Antigen Receptor (CAR) mesenchymal stem cells (MSCs) and their use in treatment of cardiovascular diseases. This technology will use engineered MSCs capable of homing toward infarcted heart tissue. Background: Cardiovascular disease is the leading cause of death in the United States. There are multiple treatments...
Published: 1/7/2025   |   Inventor(s): Youngwook Won, Byeong Hyun Cha, David Bull
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Heart and Vascular, Technology Classifications > Life Sciences > Stem Cells, Technology Classifications > Life Sciences > Therapeutics
Accurate and real-time bimanual control for surgical robots
A technology that detects and classifies coordinated two-hand movements in robotic surgery by analyzing movement patterns and symmetries, ensuring accurate real-time control despite noise for improved interaction in surgical robots. Background In robotic-assisted surgery, precise bimanual coordination is crucial for enhancing surgical outcomes and...
Published: 1/7/2025   |   Inventor(s): Ann Majewicz Fey, Jacob Boehm, Nicholas Fey
Keywords(s):  
Category(s): Life sciences > Medical technology
Advanced multi-channel controlled pneumatic printheads for 3D printing and particle fabrication
MAGIC printheads are customizable multi-channel pneumatic systems for 3D printing that create precise pharmaceutical and biological micro-particles. They enable controlled mixing and extrusion, accommodate various materials, and enhance drug delivery and biomedical applications. Background Producing micro- and nanoparticles for pharmaceutical and...
Published: 1/7/2025   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang, Faez Alkadi
Keywords(s):  
Category(s): Life sciences > Therapeutics > Manufacturing platform
Method for Repurposing FDA-approved Therapeutics & Composition for Treating Mesothelioma
The amount of time and money that goes into getting a drug from initial discovery to FDA approval is substantial, typically involving at least 10 years and hundreds of millions of dollars. Because of this, there has been a growing interest in repurposing drugs which have previously been approved for human use, particularly since their MOA as well as...
Published: 1/7/2025   |   Inventor(s): Chris Plaisier, Sierra Wilferd, Choung Hoang
Keywords(s): Cancer, Drug, Drug Discovery
Category(s): Pharmaceuticals, Cancer, Cancer Therapeutics, Artificial Intelligence/Machine Learning, Computing & Information Technology, Life Science (All LS Techs)
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