Search Results - design

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Floxed Targeted Mouse Strain for Use in Conditional Deletion of the Irf8 Gene
IRF8, a member of interferon regulatory factor (IRF) family of transcription factors is a novel intrinsic transcriptional inhibitor of TH17-cell differentiation. TH17-cells are believed to be involved in the pathogenesis of various autoimmune/inflammatory diseases. These materials could be used to help define patterns of gene expression important for...
Published: 7/25/2024   |   Inventor(s): Herbert Morse
Keywords(s): Approved, Conditional, Deletion, Design, Development, Gene, Generate, IRF8, Knockout, Listed LPM Vepa as of 4/15/2015, Mouse, Need, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, RECOGNIZED, RXXXXX, Strain, Used
Category(s): Collaboration Sought > Collaboration, Application > Research Materials
A3 Adenosine Receptor Agonists to Treat Chemotherapy-induced Peripheral Neuropathy
This invention claims species-independent agonists of A3AR, specifically (N)-methanocarba adenine nucleosides and related pharmaceutical compositions. The A3 adenosine receptor (A3AR) subtype has been linked with helping protect the heart from ischemia, controlling inflammation, and regulating cell proliferation. Agonists of the human A3AR subtype...
Published: 4/8/2024   |   Inventor(s): Dilip Tosh, Kenneth Jacobson
Keywords(s): 2-Arylethynyl, A3, ADENOSINE, CB3CXX, CB3XXX, CBXXXX, CXXXXX, Design, N-Methanocarba, Nucleosides, Receptor-Selective, Structure-based
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Oncology, Application > Therapeutics
Single Channel MRI Guidewire
The invention offered for licensing and commercial development is in the field of Interventional Magnetic Resonance Imaging (“iMRI”). More specifically the invention discloses a guidewire for magnetic resonance imaging with a single channel design to reduce complexity and to provide conspicuous tip visibility under MRI. In the design of the present...
Published: 7/25/2024   |   Inventor(s): Ozgur Kocaturk, Christina Saikus, Merdim Sonmez
Keywords(s): AA3BXX, AA3XXX, AAXXXX, Active, AXXXXX, CHANNEL, Conspicuous, Design, Guidewire, MRI, SHAFT, Single, Tip, Visibility
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Species-Independent A3 Adenosine Receptor Agonists Which May Be Useful for Treating Ischemia, Controlling Inflammation, and Regulating Cell Proliferation
This invention claims species-independent agonists of A3AR, specifically (N)-methanocarba adenine nucleosides and pharmaceutical compositions comprising such nucleosides. The A3 adenosine receptor (A3AR) subtype has been linked with helping protect the heart from ischemia, controlling inflammation, and regulating cell proliferation. Agonists of the...
Published: 7/25/2024   |   Inventor(s): Artem Melman, Kenneth Jacobson
Keywords(s): 5'Uronamides, A3, ADENOSINE, AGONISTS, Design, IA3XXX, IAXXXX, IB1XXX, IBXXXX, IXXXXX, N-Methanocarba, OB1XXX, OBXXXX, OXXXXX, Receptor-Selective, Species-Independent
Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Ophthalmology, TherapeuticArea > Cardiology, TherapeuticArea > Immunology, Application > Diagnostics, Application > Research Materials
Hydrophobic Papers Via Metal-Ion Induced Wettability Alteration, Application, And Preparation Thereof
Overview of Technology This technology is a solution to the permeability of conventional paper, by making it hydrophobic through the application of hydrophobic properties. Technology Description This technology uses a metal-ion modification method to convert conventional paper (eg. Newspapers, Copy paper, packing paper, tissue paper and kraft paper)...
Published: 10/18/2023   |   Inventor(s): Xuefeng Zhang, Oshani Rathnayaka Mudiyanselage
Keywords(s): Agriculture, Design, Food, Forestry, Materials
Category(s): Materials
A New Design of Nasal Swab
**ROYALTY-FREE READY TO SIGN LICENSE** NU 2020-078 INVENTORS Matthew Grayson* Jun Peng Jiaxing Huang Guillermo Ameer Nancy Rivera Bolanos SHORT DESCRIPTION Design of a low-cost and efficiently fabricated alternate nasal swab for COVID-19 and other viral testing BACKGROUND The 2020 COVID-19 global pandemic has put tremendous stress on the healthcare...
Published: 9/12/2024   |   Inventor(s):  
Keywords(s): COVID-19, Design, Diagnostics, Health & Safety, Medical device
Category(s): Life Sciences > Healthcare Devices, Tools & IT