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Search Results - dendritic+cells
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A Dendritic Cell Vaccine to Immunize Cancer Patients Against Mutated Neoantigens Expressed by the Autologous Cancer
Abstract: Vaccines against non-viral cancers target mainly differentiation antigens, cancer testis antigens, and overexpressed antigens. One common feature to these antigens is their presence in central immunological tolerance. Using these vaccines, T cells underwent depletion of high avidity clones directed against such antigens. This depletion can...
Published: 4/8/2024
|
Inventor(s):
Gal Cafri
,
Paul Robbins
,
Jared Gartner
,
Steven Rosenberg
Keywords(s):
CANCER
,
Dendritic cells
,
Immunotherapy
,
Neoantigens
,
Rosenberg
,
T Cells
,
vaccines
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
,
Application > Vaccines
Compositions to Enhance Vaccine Efficacy on Mucosal Surfaces
Targeting moDC to Improve Mucosal Surface ProtectionThis composition targets a subset of
dendritic cells
that mediate cyclic dinucleotide adjuvant activity, thereby improving mucosal surface protection and response to vaccines. In the 20th century, immunization has allowed us to control several life threatening diseases such as measles, whooping cough,...
Published: 9/3/2021
|
Inventor(s):
Keywords(s):
Dendritic Cells
,
mucosal
,
prevention
,
Vaccine
,
vaccine adjuvant
Category(s):
Technology Classifications > Human Health Care > Therapeutics