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Search Results - jared+gartner
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Machine Learning Model for the Prioritization of Cancer Neoepitopes
Summary: The National Cancer Institute (NCI) seeks licensees for a machine learning algorithm that scores epitopes for likelihood of reactivity in order to create personalized effective immunotherapy. Description of Technology: Success in immunotherapy is often attributable to the reactivity of patient T-cells to specific mutated peptide(s) found...
Published: 12/20/2024
|
Inventor(s):
Jared Gartner
,
Paul Robbins
,
Steven Rosenberg
Keywords(s):
Category(s):
Application > Research Materials
,
TherapeuticArea > Oncology
,
Collaboration Sought > Licensing
A Dendritic Cell Vaccine to Immunize Cancer Patients Against Mutated Neoantigens Expressed by the Autologous Cancer
Abstract: Vaccines against non-viral cancers target mainly differentiation antigens, cancer testis antigens, and overexpressed antigens. One common feature to these antigens is their presence in central immunological tolerance. Using these vaccines, T cells underwent depletion of high avidity clones directed against such antigens. This depletion can...
Published: 4/8/2024
|
Inventor(s):
Gal Cafri
,
Paul Robbins
,
Jared Gartner
,
Steven Rosenberg
Keywords(s):
CANCER
,
Dendritic cells
,
Immunotherapy
,
Neoantigens
,
Rosenberg
,
T Cells
,
vaccines
Category(s):
Collaboration Sought > Collaboration
,
Collaboration Sought > Licensing
,
TherapeuticArea > Oncology
,
Application > Vaccines