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Search Results - carl+june
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Lipid nanoparticle-based mRNA delivery for CAR T-cell engineering
A library of ionizable lipid nanoparticles (LNPs) was screened for ability to deliver mRNA to T-cells, leading to an optimized LNP formulation for delivery of mRNA to T-cells. This thereby enhances the ability to generate transient chimeric antigen receptor (CAR)-expressing T-cells for cancer immunotherapy. Problem: Chimeric antigen receptor (CAR)...
Published: 1/23/2024
|
Inventor(s):
Margaret Billingsley
,
Carl June
,
Nathan Singh
,
Michael Mitchell
Keywords(s):
Bioengineering
,
COVID-19
,
Drug Delivery
,
Immunology
,
Immunotherapy
Category(s):
Technology Classifications > Therapeutics