Search Results - bin+he

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Sensitive Point-of-Care miRNA Detection Using a One-Pot, Isothermal Assay
Rapid, RNA Extraction-Free Detection of miRNAs Biomarkers for Accurate Cancer Diagnosis and Prognosis This CRISPR-Cas12a-based assay allows for the rapid, sensitive detection of microRNAs using a one-pot, isothermal process. MicroRNAs(miRNAs) are endogenous and short, non-coding single-stranded RNAs. They participate in various biological functions...
Published: 3/4/2025   |   Inventor(s): Yong Zeng, He Yan
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Diagnostics, Technology Classifications > Veterinary > Diagnostics
Volumetric Analysis of Multi-Dimensional Images
Summary: UCLA investigators have identified an effective and accurate algorithm for calculating the volume and surface of irregularly shaped 3D structures from points selected on an image. This method can be used to calculate geometric information for a wide range of multi-dimensional objects and has been tested accurately on calculating the size of...
Published: 2/14/2025   |   Inventor(s): Ai-Chi Chien, Bin Dong, Yu Mao, Stanley Osher
Keywords(s):  
Category(s): Software & Algorithms > Image Processing, Software & Algorithms > Artificial Intelligence & Machine Learning, Medical Devices, Medical Devices > Hospital Systems, Medical Devices > Monitoring And Recording Systems, Medical Devices > Medical Imaging
Combination Cancer Therapy Methods and Agents (UCLA Case No. 2024-084)
UCLA researchers from the Department of Medicine, Pathology, & Laboratory Medicine and Molecular & Medical Pharmacology have identified a novel cell-based therapy that leads to enhanced immunotherapy efficacy and overcomes treatment resistance to immune checkpoint blockade in non-small cell lung cancer. BACKGROUND: Non-small cell lung cancer...
Published: 2/14/2025   |   Inventor(s): Bin Liu, Steven Dubinett
Keywords(s): anti-tumor immunity, cell-based therapy, Immune checkpoint blockade, Immunotherapy, non-small cell lung cancer, treatment resistance, Tumor microenvironment, Vaccines
Category(s): Therapeutics > Oncology, Therapeutics > Immunology And Immunotherapy, Therapeutics > Respiratory And Pulmonary
Non-Invasive, Early-Stage Liver Fibrosis Diagnostic
Description This technology is a cutting-edge non-invasive liver fibrosis detection technology, a revolutionary advancement in the early diagnosis of liver fibrosis. Detecting liver fibrosis early is crucial because it helps address and potentially prevent the progression of liver diseases that can lead to more severe conditions such as cirrhosis,...
Published: 3/12/2025   |   Inventor(s): Yi Jiang, Hao Chen, Sergey Klimov, Bin Zhang
Keywords(s): Liver Disease Detection
Category(s): Diagnostic, Imaging
Sensitive and Economic RNA Virus Detection Using a Novel RNA Preparation Method
Abstract: DNA or RNA-based diagnostic tests for infectious diseases are critical in modern medicine. The current gold standard for COVID-19 detection is testing SARS-CoV-2 viral RNA by quantitative reverse transcription Polymerase Chain Reaction (RT-qPCR). This method involves patient sample collection with a nasopharyngeal swab, storage of the swab...
Published: 4/8/2024   |   Inventor(s): Bin Guan, Robert Hufnagel
Keywords(s): Biomarker, Chelating Resin, Chelex Resin, COVID, COVID-19, DNA/RNA diagnostic test, Extraction-free Detection, Infectious Diseases, SARS-CoV-2, virus
Category(s): TherapeuticArea > Oncology, Application > Diagnostics, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Collaboration Sought > Licensing
SARS-COV-2 papain-like protease inhibitors as antivirals
Novel compounds and their use as an inhibitor for SARS-CoV-2. Invention Summary: Two oral SARS-CoV-2 antivirals are available, molnupiravir and Paxlovid. However, the limited efficacy, drug-drug interaction, and drug resistance are main challenges facing these two drugs. Additional oral antivirals with novel mechanisms of actions are clearly needed....
Published: 4/9/2025   |   Inventor(s): Jun Wang, Edward Arnold, Francesc Ruiz Figueras, Prakash Jadhav, Bin Tan, Ahmadullah Ansari, Ashima Chopra
Keywords(s): Antiviral, Small molecules
Category(s): Technology Classifications > COVID-19, Technology Classifications > Infectious Disease, Technology Classifications > Therapeutics, Technology Classifications > Healthcare & Life Sciences
LOW COST BEAM-EXPANDING RELAY LENS
LOW COST BEAM-EXPANDING RELAY LENS Researchers at CZ Biohub San Francisco have developed a laser scanning microscope, with significantly reduced complexity and cost, at great benefit to researchers and instrument manufacturers. Optical intervention accompanied with image acquisition of a biological sample using a laser beam scanning microscope is...
Published: 5/18/2023   |   Inventor(s): Hirofumi Kobayashi, Loic Royer, Bin Yang
Keywords(s): Cylindrical Lens, Laser, Microscope, Mirror, Optics, Scanning
Category(s): Technology Classifications > Engineering
Biosensors for Continuous Detection of Analytes
Diagnosing and monitoring diseases and health often requires detecting and measuring concentrations of one or more analytes in a patient. Frequent trips to a healthcare facility are onerous and expensive and at home testing is painful, sometimes laborious and time consuming. All of this may lead to a lack of regular testing, and could mean missed diagnoses...
Published: 4/2/2025   |   Inventor(s): Jeffrey LaBelle, Bin Mu, David Probst
Keywords(s): Bio-Technology, Drug Discovery, Medical Devices and Imaging, Therapeutics
Category(s): Advanced Materials/Nanotechnology, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Life Science (All LS Techs), Medical Diagnostics/Sensors
Lebesgue-Sampling-based Deep Learning for Battery Diagnosis and Prognosis
Reference #: 01603 The University of South Carolina is offering licensing opportunities for Lebesgue-Sampling-based Deep Learning for Battery Diagnosis and Prognosis Background: Accurate and efficient modeling of battery degradation is of great challenge and is becoming more and more complex for batteries in modern applications. Traditional degradation...
Published: 5/16/2023   |   Inventor(s): Bin Zhang, Guangxing Niu
Keywords(s): Deep belief network, Diagnosis and prognosis, Fault dynamic model, Lebesgue sampling, Lithium-ion battery, Particle filter, Uncertainty management
Category(s): Engineering and Physical Sciences, Energy
Hybrid Rotating Machinery Fault Diagnosis and Prognosis
Reference #: 01570 The University of South Carolina is offering licensing opportunities for Hybrid Rotating Machinery Fault Diagnosis and Prognosis Background: Bearing faults are the top contributor to the failure of rotating machinery systems. In wind energy systems, about 80% of gearbox failures are caused by bearing faults. According to verified...
Published: 8/22/2024   |   Inventor(s): Guangxing Niu, Bin Zhang
Keywords(s): Continuous wavelet transform, convolutional neural network, Fault model selection, Particle filter, Rotating machinery systems, STP estimation
Category(s): Engineering and Physical Sciences
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