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Search Results - yi-tsung+lu
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Precision cellular imaging for advanced biological analysis
A novel DNA-based imaging technique enabling visualization of 3D cellular components with super-resolution. Background Super-resolution microscopy has revolutionized biological research by providing finer details beyond the diffraction limit of conventional microscopy. A particular challenge in this field is the visualization of small and dynamic...
Published: 3/4/2025
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Inventor(s):
Yi Lu
,
Quanbing Mou
Keywords(s):
Category(s):
Life sciences > Imaging
,
Life sciences > Research tools > Tool/assay/screening platform
DNAzyme sensor for selective manganese ion detection in biological systems
A selective DNAzyme-based fluorescent sensor detects manganese ions in cells by lighting up when Mn²⁺ binds, allowing precise monitoring of manganese levels for biological research and potential therapies. Background Manganese (Mn²⁺) is an essential trace element integral to numerous biological processes, acting as a vital cofactor for enzymes...
Published: 1/31/2025
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Inventor(s):
Yi Lu
,
Zhenglin Yang
,
Huanhuan Fan
Keywords(s):
Category(s):
Life sciences > Biomaterials
DNAzyme fluorescent sensors for bioselective imaging of Fe²⁺ and Fe³⁺ ions
Developed DNAzyme-based fluorescent sensors that specifically detect and image Fe2⁺ and Fe3⁺ ions in living cells, enabling the study of iron dynamics in biological processes and diseases like Alzheimer’s. Background Iron ions, specifically Fe2⁺ and Fe3⁺, are essential for numerous biological processes, including oxygen transport, DNA synthesis,...
Published: 1/31/2025
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Inventor(s):
Yi Lu
,
Seyed-Fakhreddin Torabi
,
Yuting Wu
,
Ryan Lake
,
Zhenglin Yang
,
Peiwen Wu
,
Whitney Lewis
,
Jacqueline Van Stappen
,
Xiangli Shao
Keywords(s):
Category(s):
Life sciences > Biomaterials
DNA aptamer technology for Coenzyme A detection and cellular imaging
Researchers developed a DNA aptamer that specifically targets Coenzyme A, enabling easy and accurate detection in cells. This technology is more specific and simpler than current methods, supporting diagnostics, research, and treatments for diseases involving CoA imbalance. Background The field of biochemical research and medical diagnostics increasingly...
Published: 1/14/2025
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Inventor(s):
Yi Lu
,
Whitney Lewis
,
Yuan Ma
Keywords(s):
Category(s):
Life sciences > Therapeutics > Drug screening
,
Life sciences > Research tools > Tool/assay/screening platform
ARPLA: a revolutionary glycoRNA imaging tool with precision and power
Background/problem Glycosylated RNAs (GlycoRNAs) are a newly discovered class of molecules involved in glycosylation. They have been found on the surfaces of various cell types, organisms, and species, further advancing the role of RNA in biological processes. Despite this, our knowledge of glycoRNAs and their functions remains limited, primarily...
Published: 7/26/2024
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Inventor(s):
Yi Lu
,
Yuan Ma
,
Weijie Guo
,
Quanbing Mou
Keywords(s):
Category(s):
Life sciences > Research tools > Tool/assay/screening platform
A Linear Coding Method for Communication in Networks
Leveraging data from generic sensing devices to enable accurate crowd-sourced road geometry estimation and enhanced vehicular state estimations. Background: In the transportation industry, key challenges revolve around obtaining road geometry data and reliable vehicular state estimation using generic sensing devices. These devices, while widely...
Published: 1/28/2025
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Inventor(s):
Abhishek Gupta
,
Chunming Qiao
,
Lu Su
,
Sateesh Addepalli
Keywords(s):
Featured
,
Technologies
Category(s):
Campus > University at Buffalo
,
Technology Classifications > Engineering
Deep Residual Inception Encoder-Decoder Network for Amyloid PET Harmonization
It is estimated that more than 6 million Americans may have dementia caused by Alzheimer’s disease (AD). Currently, AD is ranked as the seventh leading cause of death in the US. While several proteins have been implicated in AD, two, beta-amyloid and tau, are considered the defining pathologies of AD. Amyloid and tau imaging has subsequently become...
Published: 2/13/2025
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Inventor(s):
Fei Gao
,
Yi Su
,
Jay Shah
,
Teresa Wu
Keywords(s):
Category(s):
Computing & Information Technology
,
Imaging
,
Life Science (All LS Techs)
,
Medical Imaging
,
Neurodegenerative Disease Technologies
Identification of a Platform to Identify Tumor-Specific T Cell Receptors (UCLA Case No. 2022-082)
SUMMARY: Researchers from UCLA’s Department of Neurosurgery and Pharmacology have developed a rapid discovery platform for the identification of tumor-specific T cell receptors to aid in more personalized and potent immunotherapy for glioblastoma. BACKGROUND: Over the past several years, immunotherapy, or therapies that enlist and strengthen...
Published: 2/14/2025
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Inventor(s):
Robert Prins
,
Alexander Lee
,
Lu Sun
,
David Nathanson
Keywords(s):
Category(s):
Therapeutics
,
Therapeutics > CNS and Neurology
,
Therapeutics > Oncology
,
Therapeutics > Immunology And Immunotherapy
,
Therapeutics > Oncology > Oncology Immunotherapy
2015-172 VERY-SMALL-NUCLEAR CIRCULATING TUMOR CELL (VSNCTC) AS A DIAGNOSTIC BIOMARKER OF VISCERAL METASTASIS IN ADVANCED PROSTATE CANCER
Very-Small-Nuclear Circulating Tumor Cell (vsnCTC) as a Diagnostic Biomarker of Visceral Metastasis in Advanced Prostate CancerTech ID: 30306 / UC Case 2015-172-2SUMMARYUCLA researchers in the Department of Molecular and Medical Pharmacology have identified a novel biomarker that can be used to diagnose prostate cancer patients for the presence of visceral...
Published: 2/14/2025
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Inventor(s):
Hsian-Rong Tseng
,
Jiaoti Huang
,
Zunfu Ke
,
Ker-Chau Li
,
Min Song
,
Edwin Posadas
,
Yi-Tsung Lu
,
Jake Lichterman
,
Leland Chung
,
Jiefu Chen
Keywords(s):
Diagnostic Markers & Platforms
,
Diagnostic Platform Technologies (E.G. Microfluidics)
,
Life Science Research Tools
,
Oncology
Category(s):
Life Science Research Tools
,
Diagnostic Markers
,
Platforms > Diagnostic Platform Technologies
,
Therapeutics > Oncology
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024
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Inventor(s):
Soung Chang Liew
,
Lu LU
,
Lizhao You
Keywords(s):
Network Coding
,
Wireless Local Area Network
Category(s):
Information and Communications Technology
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