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Search Results - vijayan+ramachandran
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C41 Analogs
This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
Wei Wang
,
Rui Chang
,
Vijayan Ramachandran
,
Patrick Ronaldson
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Neurology
,
Technology Classifications > Life Sciences > Nutraceuticals
,
Technology Classifications > Life Sciences > Small Molecules
,
Technology Classifications > Life Sciences > Therapeutics
,
Technology Classifications > Life Sciences > Biologics
Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. <.HDBackground>Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases,...
Published: 1/29/2024
|
Inventor(s):
Li Niu
,
Zhen Huang
,
Yan Han
,
Congzhou Wang
,
Jae Seon Park
Keywords(s):
RNA
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus
,
Campus > University at Albany
18F-Radiotracer for Oxidative Stress PET Imaging
Summary: An 18F-radiotracer able to detect oxidative stress via positron emission tomography (PET). What A radiotracer based on 18F-labelled molecular probe that allows imaging of Reactive Oxygen Species (ROS) stress. It can be used for the early diagnosis of cardiovascular, neurodegenerative diseases, and cancers and inflammatory conditions. ...
Published: 9/3/2024
|
Inventor(s):
Ran Yan
Keywords(s):
Category(s):
Diagnostics
,
Research Tools - Imaging
Novel Compounds Inhibiting COVID-19 Replication
This technology is three potential pharmacological treatment options for COVID-19. The inventors identified three compounds, two naturally occurring and one small-molecule. These compounds target and inhibit the main 3CL protease that is essential to the replication of SARS-CoV-2 and have been shown to be effective against the virus in vitro. Background: In...
Published: 4/3/2023
|
Inventor(s):
Rui Chang
,
Dominik Schenten
,
Patrick Ronaldson
,
Yanyun Liu
,
Vijayan Ramachandran
Keywords(s):
Category(s):
Technology Classifications > Life Sciences
Combinations for the Treatment of Neurodegeneration
Researchers at the University of Arizona have researched new formulations and combinations of compounds for the treatment of Alzheimer’s disease. Developing a novel computational system allowed the inventors to identify several therapeutic targets of single cell type and whole bulk tissue that contribute to Alzheimer's disease. These therapeutic...
Published: 4/3/2023
|
Inventor(s):
Rui Chang
,
Patrick Ronaldson
,
Wei Wang
,
Vijayan Ramachandran
,
Yanyun Liu
,
Qianying He
Keywords(s):
Category(s):
Technology Classifications
,
Technology Classifications > Life Sciences
A Pashto-English Dictionary
This technology is a multi-use dictionary that contains Pashto entries with corresponding English words, allowing individuals to learn either Pashto or English. Background: Current versions of online Pashto dictionaries have varying amounts of Pashto entries with English translations, many of which have no verification of their learning materials,...
Published: 4/3/2023
|
Inventor(s):
Yan Han
,
Atifa Rawan
Keywords(s):
Category(s):
Technology Classifications > Creative Works
,
Technology Classifications > Software & Information Technology > Web & Internet