Search Results - patrick+ronaldson

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C41 Analogs
This invention generally relates to neurodegenerative diseases and conditions, such as Alzheimer’s disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 12/5/2024   |   Inventor(s): Wei Wang, Rui Chang, Vijayan Ramachandran, Patrick Ronaldson
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Nutraceuticals, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Biologics
Novel Compounds Inhibiting COVID-19 Replication
This technology is three potential pharmacological treatment options for COVID-19. The inventors identified three compounds, two naturally occurring and one small-molecule. These compounds target and inhibit the main 3CL protease that is essential to the replication of SARS-CoV-2 and have been shown to be effective against the virus in vitro. Background: In...
Published: 4/3/2023   |   Inventor(s): Rui Chang, Dominik Schenten, Patrick Ronaldson, Yanyun Liu, Vijayan Ramachandran
Keywords(s):  
Category(s): Technology Classifications > Life Sciences
Combinations for the Treatment of Neurodegeneration
Researchers at the University of Arizona have researched new formulations and combinations of compounds for the treatment of Alzheimer’s disease. Developing a novel computational system allowed the inventors to identify several therapeutic targets of single cell type and whole bulk tissue that contribute to Alzheimer's disease. These therapeutic...
Published: 4/3/2023   |   Inventor(s): Rui Chang, Patrick Ronaldson, Wei Wang, Vijayan Ramachandran, Yanyun Liu, Qianying He
Keywords(s):  
Category(s): Technology Classifications, Technology Classifications > Life Sciences