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Topical Sodium Nitrate Ointment for Sickle Cell Disease
Abstract: Chronic leg ulcers are a debilitating vasculopathic complication for some patients with sickle cell disease (SCD). Prevalence of leg ulcers varies based on age and geographic location; about 5-10% of all SCD patients may suffer leg ulcers. These leg ulcers are painful, result in infections, hospitalization, disability, and negatively impact...
Published: 4/8/2024   |   Inventor(s): Haksong Jin, George Grimes, Deborah Sperling, Gopal Potti, Caterina Minniti-Crouch, Gregory Kato
Keywords(s): Blood Disorder, CREAM, Haksong, nitric oxide, Ointment, SCD, sickle cell disease, Sodium Nitrate, TOPICAL, Topical Therapeutic, Vascular Ulcers, Wound healing
Category(s): TherapeuticArea > Endocrinology, Application > Therapeutics, TherapeuticArea > Cardiology, Collaboration Sought > Licensing
Pre-Biotic Formulation of Topical Chemicals for Use on Human Skin
Atopic dermatitis (AD) is a common, recurrent, chronic inflammatory skin disease that is a cause of considerable economic and social burden. It is one of the most prevalent skin disorders, affecting ~25% of children in developed and developing countries and is expected to continue to escalate. This increased rate of incidence has changed the focus of...
Published: 7/25/2024   |   Inventor(s): Carlo Castillo, Ian Myles
Keywords(s): CHEMICALS, FORMULATION, Human, Pre-biotic, SKIN, TOPICAL
Category(s): Collaboration Sought > Collaboration
Topical Treatment for Raynaud’s Phenomenon Targets Cold Receptor
Project ID: D2015-43IP Status: PCT Patent application Invention Description and Novelty: Systemic sclerosis (also known as scleroderma, SSc) is an autoimmune connective tissue disease that is characterized by the presence of Raynaud’s phenomenon (RP) that manifests by repeated episodes of vasospasm of the distal arteries...
Published: 6/18/2024   |   Inventor(s): Bashar Kahaleh, Sai HS Boddu, Nezam Altorok, Vivek Nagaraja
Keywords(s): Autoimmune, Raynaud's, Schlerosis, Skin, Topical, Treatment
Category(s): Inflammation & Immunity