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Search Results - technology+classifications+%3e+research+tools+%3e+antibodies
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Endoglin Antibody
This technology is the use of endoglin-specific antibodies to enhance the detection process of certain cancers, offering a more precise and reliable approach to identifying cancer-related variants of endoglin. Directed toward an antibody to a mutated endoglin protein, this antibody provides methods and compositions for detecting splice variants of the...
Published: 5/30/2025
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Inventor(s):
Nam Lee
Keywords(s):
Category(s):
Technology Classifications > Healthcare Portfolios > Oncology
,
Technology Classifications > Life Sciences > Biomarkers
,
Technology Classifications > Research Tools > Antibodies
Monoclonal Antibodies against Heterogeneous Nuclear Ribonuclear Proteins (hnRNP) m3/4 & m1-4
Recognize hnRNP-M3 As WellHeterogeneous nuclear ribonucleoproteins (hnRNPs), which directly bind to nascent RNA polymerase II transcripts, play an important role in both transcript-specific packaging and alternative splicing of pre-mRNAs. These "M proteins" are pre-mRNA-binding proteins in vivo, and they bind to poly(G) and poly(U) RNA homopolymers...
Published: 7/12/2022
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Inventor(s):
Maurice Swanson
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Others
Shelf-Stable Reagent for Bioconjugation and Protein Labeling
This invention is a new class of amine-reactive, water-stable, small molecules for use as probes, reagents, or bioconjugates. These molecules are lysine-reactive and conjugate quickly without the need for coupling reagents or catalysts. The molecules are simple to synthesize and purify, with high yields. These materials selectively react with lysine...
Published: 6/20/2024
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Inventor(s):
John Jewett
,
Garrett Davis
,
Holly Sofka
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Screening assays
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Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Protein
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Technology Classifications > Research Tools > Reagents
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Technology Classifications > Life Sciences > Diagnostics
Monoclonal Antibody against Connective Tissue Growth Factor
Belongs to the CTGF/Cyr61/Cef10/NOVH Protein FamilyConnective Tissue Growth Factor (CTGF) belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF (Connective Tissue Growth factor) is a cysteine-rich, matrix-associated, heparin-binding protein. In vitro,...
Published: 6/27/2021
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Inventor(s):
Gregory Schultz
,
Daniel Gibson
,
John Azeke
,
Priscilla Phillips
,
Edith Sampson
,
Paulette Robinson
Keywords(s):
Antibody
,
CTGF
,
Elisa
,
Immunochemistry
,
Monoclonal
,
reagent
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Biological Materials
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Technology Classifications > Research Tools > Others
Monoclonal Antibody against Trinucleotide TNGW1 (TNRC6G)
RNA Interference with GW182 Results in Translation SuppressionRNA interference (RNAi), triggered by small interfering RNA and microRNA (miRNA), is a potent mechanism in post-transcriptional regulation for gene expression. GW182 is a 182kDa protein which binds to the 3’ untranslated region of mRNA targeted by miRNA and resulting in translation...
Published: 2/22/2024
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Inventor(s):
Edward Chan
,
Songqing Li
Keywords(s):
Antibody
,
GW182
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Human
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Monoclonal
,
reagent
,
RNA Interence
,
Translational Repression
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Biological Materials
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Technology Classifications > Research Tools > Others
Monoclonal Antibody against Phosphorylated RAX/PACT Protein
Peptide Compose of RAX Amino Acides Used as Antigen to AntibodyMurine RAX (PKR Activator X) protein and its human ortholog PACT (Protein Activator of Interferon-induced Protein Kinase) are the only known cellular activators of the interferon-induced dsRNA-dependent protein kinase, PKR. RAX and PACT are 98% identical in amino acid sequence. In addition,...
Published: 7/12/2022
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Inventor(s):
Richard Bennett
,
William May
Keywords(s):
Antibody
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Apoptosis
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Monoclonal
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Monoclonals
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Mouse
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PACT
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RAX
,
Tumor
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Biological Materials
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Technology Classifications > Research Tools > Others
Monoclonal antibodies targeting enzyme involved in silencing mRNA, proteins associated with liver cancer, tumor growth and post-transcription gene silencing
Monoclonal Antibody against p62/IGF2BP2p62/IGF2BP2 is a cytoplasmic mRNA binding protein which binds to mRNA encoding IGF-II and may be involved in hepatic carcinogenesis because autoantibodies are found in a large percentage of patients with hepatocellular carcinoma. MAb were generated using the full length recombinant human protein as antigen. Monoclonal...
Published: 7/12/2022
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Inventor(s):
Edward Chan
Keywords(s):
Antibody
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Human
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Monoclonals
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RNA
,
Tumor
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Biological Materials
,
Technology Classifications > Research Tools > Others
Monoclonal Antibody against CUGBP2/ETR-3 Proteins
Recognizes Both Human and Mouse CUGBP2/ETR-3 Proteins but Does Not Bind to Other CELF Family MembersCUGBP2/ETR-3 is a member of the CELF family of pre-mRNA alternative splicing factors which play an important role in the appearance of specific protein isoforms during postnatal development. The CELF family has also been implicated in the neuromuscular...
Published: 7/12/2022
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Inventor(s):
Maurice Swanson
Keywords(s):
Antibody
,
COX2
,
CUGBP2
,
Monoclonals
,
Myotonic Dystrophy
,
RNA Splicing
,
RNA Turnover
Category(s):
Technology Classifications > Research Tools > Antibodies
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Technology Classifications > Research Tools > Biological Materials
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Technology Classifications > Research Tools > Others
Monoclonal Antibody against Human Calcium-Sensing Receptor
Determines Extracellular Levels of Calcium to Determine Intake Levels of Calcium for CellsThe calcium-sensing receptor detects extracellular levels of calcium to determine the intake levels of calcium for cells. A monoclonal antibody was raised against the extracellular N-terminus of the human calcium-sensing receptor and recognizes human, mouse, rat,...
Published: 7/12/2022
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Inventor(s):
Richard Miller
Keywords(s):
Antibody
,
Calcium-sensing Receptor
,
Cell signaling
,
G protein
,
Monoclonals
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Biological Materials
,
Technology Classifications > Research Tools > Others
Monoclonal Antibodies against Limulus Visual Arrestin
Antibodies Are Specific for Limulus-Wide SpeciesThese monoclonal antibodies (4 different hybridomas) were raised against the N-terminal half of recombinant Limulus (horseshoe crab) visual arrestin, a protein that interrupts light-activated signal transduction in the eye, causing an autoimmune eye disorder. Antibodies are specific for Limulus-wide species;...
Published: 2/22/2024
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Inventor(s):
Barbara-Anne Battelle
,
Wesley Smith
Keywords(s):
Category(s):
Technology Classifications > Research Tools > Antibodies
,
Technology Classifications > Research Tools > Biological Materials
,
Technology Classifications > Research Tools > Others
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