Search Results - wesley+smith

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Modified Arrestin-1 Variants for Enhancing Photoreceptor Survival in Retinal Disease
Binds to Enolase-1 without Inhibiting its Catalytic Activity, Slowing Retinal Degradation and Alleviating Vision Loss These arrestin-1 variants slow retinal degradation by reducing the inhibitory effects of enolase-1 activity, enhancing photoreceptor survival in retinal disease. Inherited retinal diseases (IRDs) affect over two million people worldwide,...
Published: 1/30/2023   |   Inventor(s): Wesley Smith, Astra Dinculescu, Vince Chiodo
Keywords(s):  
Category(s): Technology Classifications > Human Health Care > Gene Therapy
Monoclonal Antibodies against Limulus Visual Arrestin
Antibodies Are Specific for Limulus-Wide SpeciesThese monoclonal antibodies (4 different hybridomas) were raised against the N-terminal half of recombinant Limulus (horseshoe crab) visual arrestin, a protein that interrupts light-activated signal transduction in the eye, causing an autoimmune eye disorder. Antibodies are specific for Limulus-wide species;...
Published: 2/22/2024   |   Inventor(s): Barbara-Anne Battelle, Wesley Smith
Keywords(s):  
Category(s): Technology Classifications > Research Tools > Antibodies, Technology Classifications > Research Tools > Biological Materials, Technology Classifications > Research Tools > Others