Search Results - technology+classifications+%3e+life+sciences+%3e+therapeutics

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Peptide Therapeutic for Promoting Tumor Cell DNA Damage and Natural Killer Cell-Mediated Metastatic Surveillance
This invention is a cell-penetrating peptide therapeutic that blocks nuclear epidermal growth factor receptor (nEGFR) localization to induce tumor regression and natural killer (NK) cell-mediated metastatic surveillance of triple-negative breast cancer (TNBC). Mouse model studies demonstrated that inhibiting nEGFR trafficking induces NK cell surveillance,...
Published: 7/28/2026   |   Updated: 7/28/2026   |   Inventor(s): Joyce Schroeder, Ryan Hecksel
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics
Carpal Arch Space Augmentation (CASA) with FUFA
This invention is a radioulnar wrist compression device designed to treat carpal tunnel syndrome (CTS) involving a biomechanical approach to augment the carpal arch area. This device involves mechanisms of wrist compression for carpal arch space augmentation to alleviate median nerve compression and restore impaired neurophysiological and biomechanical...
Published: 7/27/2026   |   Updated: 7/27/2026   |   Inventor(s): Zong-Ming Li
Keywords(s):  
Category(s): Technology Classifications > Medical Devices > Therapeutic, Technology Classifications > Healthcare Portfolios > Musculoskeletal Disorders, Orthopedics/Bone, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Sensors & Controls
Artificial Intelligence Model for Prediction of Optimal Peptide Binding to Specific MHC Alleles
This technology is an artificial intelligence (AI) software platform that predicts which tumor-derived peptides are most likely to bind to a patient’s specific major histocompatibility complex (MHC) alleles. By combining tumor sequencing data with patient-specific MHC profiles, the model helps identify neoantigens for personalized cancer vaccine...
Published: 7/22/2026   |   Updated: 7/22/2026   |   Inventor(s): Michael Kuhns, Ryan Sprissler, Ryan Gutenkunst, Heng Wu
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Vaccines, Technology Classifications > Software & Information Technology > Health IT
Far-Red Light Activated Heterocyclic Carbocation Photosensitizers for Photodynamic Therapy and Immunogenic Cancer Cell Death
This invention is a novel metal-free photosensitizer platform designed for photodynamic therapy (PDT) application in cancer and pre-cancer treatment. The technology uses organic light activated particles that allow longer light wavelength and enable deeper tissue penetration compared to PDT agents. Upon irradiation with far-red light, molecules generate...
Published: 7/13/2026   |   Updated: 7/13/2026   |   Inventor(s): Thomas Gianetti
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Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Materials > Chemicals
Novel ZnO Nanowire-Based Hybrid Nanocarrier for Cancer Drug and Gene Delivery
This invention relates to a novel tri-component nanocomposite system comprising commercially available zinc oxide nanowires (ZnO NWs) functionalized to simultaneously deliver both small-molecule drugs and genetic material to cancer cells. This hybrid nanocarrier platform addresses critical limitations of current cancer therapies, including poor tumor...
Published: 5/6/2026   |   Updated: 5/6/2026   |   Inventor(s): Prashant Sharma, Mario Otto
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Diagnostics, Technology Classifications > Life Sciences > Drug Delivery, Technology Classifications > Life Sciences > Therapeutics
ERG-7 Inhibitors: Targeting the Sterol Biosynthetic Pathway
This invention relates to small molecule anti-fungal compounds, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of fungal diseases in human and veterinary subjects. In particular aspects, the invention provides inhibitors that modulate fungal sterol biosynthesis, including inhibitors of lanosterol synthase...
Published: 7/22/2026   |   Updated: 5/6/2026   |   Inventor(s): Rui Xiong, Hongmin Li, Malla Reddy Gannarapu, Divakar Indukuri, Anil Tharappel, Ke Chen, Mengjiao Ma
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Healthcare Portfolios > Respiratory & Pulmonary, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
Multi-Targeted Kinase Inhibitors Towards AML and Other Cancers
This invention relates to small-molecule compounds that are potential therapeutics for Acute Myeloid Leukemia (AML), specifically AML with the FMS-like tyrosine kinase 3 (FLT3) mutation. The compounds also show activity versus Abl kinases, platelet-derived growth factor receptor (PDGFR), and the dual-specificity tyrosine regulated/Cdc2-like (DYRK/CLK)...
Published: 7/27/2026   |   Updated: 5/6/2026   |   Inventor(s): Christopher Hulme, Alessandra Fistrovich, Samantha Rokey, Aidan McMahon, Timothy Chavez, Jennifer Carew
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Small Molecules, Technology Classifications > Life Sciences > Therapeutics
nsP2 Inhibitors: Targeting the Alphavirus nsP2 Protease
This invention relates to antiviral compounds targeting the alphavirus nsP2 protease, pharmaceutical compositions, and methods of use for the prevention, treatment, or mitigation of the Chikungunya virus. This compound selectively interferes with the essential proteolytic processing activity of nsP2, a critical step in the viral life cycle. By blocking...
Published: 7/22/2026   |   Updated: 4/29/2026   |   Inventor(s): Hongmin Li, Rui Xiong, Subodh Samrat, Malla Reddy Gannarapu, Ran Zhang, Ke Chen, Mengjiao Ma, Omar Alejandro Lozano Ramos, Divakar Indukuri, Renu Bhardwaj
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Infectious Diseases, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Life Sciences > Small Molecules
Organ-on-Chip Apparatus for Studying and Monitoring Acoustic Wave Interaction with Gas Bubbles and Disruption of Cellular Barriers
This invention relates to an ultrasound-transparent organ-on-chip platform and a method to study and monitor acoustic wave interaction with gas bubbles and disruption of cellular barriers. The invention can be used for drug screening for ultrasound gas bubble disruption of the blood-brain-barrier (BBB) for brain drug delivery and can be used as a product...
Published: 5/6/2026   |   Updated: 3/9/2026   |   Inventor(s): Jian Gu, Nabhan Fakrudin
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Neurology, Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Research Tools > Simulators and Modeling Tools, Technology Classifications > Research Tools > Screening assays
Chimeric Inhibitors
Chimeric PARP/NAMPT inhibitors have been designed to be phosphoribosylated by NAMPT (nicotinamide phosphoribosyltransferase). This modification enriches the cytotoxic adducts held within cancer cells that overexpress NAMPT and significantly increases the safety and efficacy of PARP inhibition, minimizes resistance, and promotes further cancer cell death....
Published: 7/18/2026   |   Updated: 3/4/2026   |   Inventor(s): Gregory Thatcher, Jiqiang Fu, Ganga Reddy Velma
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics, Technology Classifications > Healthcare Portfolios > Oncology
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