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Enhanced Proteomic Profiling of Human Plasma-Derived Extracellular Vesicles through Charge-Based Fractionation to Advance Biomarker Discovery Potential
Method for enhanced isolation & analysis of plasma-derived extracellular vesicles, improved biomarker discovery & disease diagnostics Background: Current methods for isolating and analyzing extracellular vesicles (EVs) from plasma face significant challenges in achieving adequate purification from abundant plasma proteins, limiting their utility...
Published: 7/22/2026   |   Updated: 6/13/2025   |   Inventor(s): Alexander Ivanov, Xianyi Su, Alan Zimmerman
Keywords(s):  
Category(s): Technology Classifications > Life Science > Drug Delivery, Technology Classifications > Life Science > Chemistry, Technology Classifications > Life Science > Bio-sensors, Technology Classifications > Life Science > Diagnostics
Methods for localizing and classifying cavitation activities based on eigen-based frequency selection
Enhancing image-guided therapeutic ultrasound: Precise detection & classification of bubble behavior for better treatment efficacy & safety Background: In therapeutic ultrasound applications, accurately detecting and classifying bubble behavior (cavitation) is crucial for optimizing treatment efficacy and safety. Current methods for passive...
Published: 7/22/2026   |   Updated: 6/13/2025   |   Inventor(s): Tao Sun, Nathan Caso
Keywords(s):  
Category(s): Technology Classifications > Life Science > Biotechnology, Technology Classifications > Life Science > Theragnostic, Technology Classifications > Computer Science > Imaging, Technology Classifications > Life Science > Diagnostics
Neuro-Behavioral Assay for Physiological Evaluation of Water-Soluble Anesthetics
Background The development and use of general anesthetics is a key aspect of modern medicine. However, the current reliance on lipid-soluble general anesthetics presents issues, particularly for elderly patients who often have increased adipose tissue and decreased body water. This demographic can respond poorly to lipid-soluble anesthetics, resulting...
Published: 7/22/2026   |   Updated: 1/17/2024   |   Inventor(s): Gunther Zupanc, David Lehotzky
Keywords(s): Anesthesiology, Assays, Chemotherapy, Drug Discovery & Development, High Throughput Screening
Category(s): Technology Classifications > Life Science > Drug Discovery, Technology Classifications > Life Science > Diagnostics, Technology Classifications > Life Science > Therapeutics
Nanopore and membrane protein dynamic multichannel measurement apparatus and fabrication method for same
INV-23089 Background: Nanopore sensing devices are integral to scientific research and applications such as DNA sequencing and protein detection. The dynamic of trans and cis user access to a membrane in such devices can, however, pose significant challenges. Fulfilling the need for multiplexed and scalable nanopore sensing systems, especially those...
Published: 7/22/2026   |   Updated: 12/20/2023   |   Inventor(s): Meni Wanunu, Ali Fallahi, Amr Makhamreh
Keywords(s): Biosensing, Drug Discovery, Microfluidics, Nanopores, Protein sequencing
Category(s): Technology Classifications > Life Science > Diagnostics, Technology Classifications > Life Science > Gene Sequencing, Technology Classifications > Physical Science > Advanced materials/Nanomaterials, Technology Classifications > Life Science > Chemistry