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Connecting multiple tRNA molecules, including in vitro transcribed as well as native tRNAs, to enable sequencing and structural applications Background: Transfer RNA (tRNA) molecules play a crucial role in biological processes, but technical limitations hinder their analysis. The short length of individual tRNAs makes them challenging to sequence...

Published: 5/26/2026 | Updated: 6/13/2025 | Inventor(s): Miten Jain, Stuart Akeson, Hugh Olsen, Robin AbuShumays, Nicolette Thomas, Mark Akeson

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Bioinformatics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering

Strategies to enhance protein translocation efficiency and smoothness through biological nanopores

Advancing protein analysis with enhanced nanopore translocation methods for single-molecule applications, single molecule proteomics Background: Accurate protein analysis is essential for advancing proteomics. Nanopore technology exhibited great promise for real-time, single-molecule protein analysis with the potential for high-throughput and cost-effective...

Published: 3/25/2026 | Updated: 6/13/2025 | Inventor(s): Meni Wanunu, Xialin Zhang, Zhuoyu Zhang

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Bio-sensors, Technology Classifications > 1. Life Science > Chemistry

Methods for single-molecule amplification of nuclear RNA

Novel technique for sorting cells based on nuclear RNA expression that enhances detection sensitivity while maintaining high sensitivity Background: Single-molecule fluorescent in situ hybridization (smFISH) stands as the gold standard for RNA visualization and quantification in cellular studies. However, its application in high-throughput methods...

Published: 5/26/2026 | Updated: 6/13/2025 | Inventor(s): Sara Rouhanifard, Yifang Liu

Keywords(s): Biology, Biomaterials, Fluorescence in situ hybridization (FISH), Imaging Technology, RNA targetting

Category(s): Technology Classifications > 1. Life Science > Bio-sensors, Technology Classifications > 1. Life Science > Chemistry, Technology Classifications > 1. Life Science > Biotechnology

Plasmid vectors for in vivo selection-free use with the probiotic E. coli Nissle

Living therapeutic patches for healing mucosal wounds in the gut Background: Inflammatory Bowel Diseases (IBD), including Crohn's disease and ulcerative colitis, are common, debilitating, and poorly treated conditions, affecting around eight million people worldwide. Current therapeutics include immunosuppressants and biologics that are often...

Published: 7/6/2026 | Updated: 6/13/2025 | Inventor(s): Neel Joshi, Ilia Gelfat, Anton Kan

Keywords(s): Gastrointestinal Disease, pMUT

Category(s): Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bio-sensors

Device for High Throughput Isolation and Cultivation of Microbial Species

A high-throughput platform for in situ microbial cultivation using diffusion chambers, enabling the growth and isolation of uncultivated species in natural environments. https://nu.technologypublisher.com/files/sites/adobestock_795674473.jpeg https://nu.technologypublisher.com/files/sites/vaibhav-1280x16001.jpeg Source Author Nabeel Adobe stock...

Published: 5/26/2026 | Updated: 10/15/2024 | Inventor(s): Slava Epstein

Keywords(s): Drug Discovery & Development, Microbiology, Singe cell

Category(s): Technology Classifications > 1. Life Science > Biotechnology

A Method for Modulating Hydrogen Sulfide Concentrations in the Human Intestine

Engineered bacteria (smart probiotics) have been developed to sense and modify harmful sulfur species and specifically hydrogen sulfide in the gut for the treatment of intestinal diseases such as IBD. https://nu.testtechnologypublisher.com/files/sites/vaibhav-1280x1600.jpeg https://nu.technologypublisher.com/files/sites/adobestock_586108897.jpeg Source:...

Published: 5/12/2026 | Updated: 8/11/2024 | Inventor(s): Benjamin Woolston, Justin Hayes

Keywords(s): Biotech, Gastrointestinal Disease, Medical/Health, Metabolic Engineering, Microbiology

Category(s): Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bio-sensors, Not in use > -Health, Not in use > -Microbiology, Not in use > -Chemistry

Mitochondria transplantation in immune effector cells using droplet microfluidics and a sorter device for activating, modulating, or inhibiting immune cell activity or any cancer or tissue cell type

Search Result Description Here Copy Image URL via instructions below Copy Image URL via instructions below INV-23048 Background: Mitochondria are intracellular organelles that power cells by maintaining cellular homeostasis and contributing to vital cellular functions. They play an instrumental role in immune cell maintenance by...

Published: 7/16/2026 | Updated: 1/17/2024 | Inventor(s): Tania Konry, Judene Thomas, Agustin De Ganzó

Keywords(s):

Category(s): Technology Classifications > 1. Life Science > Therapeutics, Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology

Site-specific Modification of Antibody through a Tranglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan

Site-specific Modification of Antibody through a Transglutaminase-mediated Conjugation of Glutamine While Maintaining the Core Glycan Technical advancement of site-specific antibody engineering creating more homogenous biologics Institute Reference: INV-21035 Background Antibodies are a predominant class of macromolecules with wide-spread...

Published: 5/26/2026 | Updated: 1/10/2022 | Inventor(s): Zhaohui Zhou, Amissi Sadiki

Keywords(s): Antibody conjugates, Endoglycosidase, Glycan remodeling, Glycoengineering, Transglutaminase

Category(s): Technology Classifications > 1. Life Science > Bioengineering/Tissue Engineering, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Diagnostics, Technology Classifications > 1. Life Science > Chemistry

Robust Self-Regeneratable Stiff Living Materials

INV-20116 Background Most biomaterials (e.g. wood, silk) found in nature are formed at ambient conditions and degrade naturally to enable a sustainable ecosystem. In contrast, the production of human-made materials (e.g. cement, plastics) requires high temperatures or harsh chemical treatments, while their non-biodegradability unfavorably affects...

Published: 5/26/2026 | Updated: 9/4/2020 | Inventor(s): Neel Joshi, Anna Duraj-Thatte, Avinash Manjula-Basavanna

Keywords(s): Biomaterials, Biotech, Environment, Living Materials, Manufacturing, Materials, Regeneration

Category(s): Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 2. Physical Science > Manufacturing, Technology Classifications > 1. Life Science > Biotechnology

Rapid, benchtop, manufacturing of microfluidic organs-on-chips with integrated electrodes using laser cut double sided adhesives, thermoplastics and inkjet printed silver electrodes

INV-18019 Background In recent years, there has been an increased interest in organs-on-chips technology as these physiological models may augment drug discovery. However, the lack of rapid, scalable, and facile manufacturing techniques limit the widespread use of organs-on-chips. Most intestine-on-a-chip models are manufactured via poly(dimethylsiloxane)...

Published: 5/26/2026 | Updated: 9/4/2020 | Inventor(s): Abigail Koppes, Sanjin Hosic, Shashi Murthy, Ryan Koppes, Jonathan Soucy

Keywords(s):

Category(s): Technology Classifications > 2. Physical Science > Manufacturing, Technology Classifications > 2. Physical Science > Advanced materials/Nanomaterials, Technology Classifications > 1. Life Science > Biotechnology, Technology Classifications > 1. Life Science > Drug Discovery

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