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A smart Neuron-Targeted Drug Delivery Platform for the treatment of brain diseases
Unmet Need: Treating brain disorders has long been hindered by the impermeability of the blood-brain barrier (BBB). Even if the drugs or nanoparticles cross the impaired BBB following brain injury or neuroinflammation, their uptake in the key cells involved in the brain diseases, especially neurons, specifically at the site of brain injury, remain the...
Published: 3/12/2025   |   Inventor(s): Anjali Sharma, Rishi Sharma, Anubhav Dhull, Aqib Dar
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry
2-deoxyglucose-based dendrimer nanomedicine for the treatment of prostate cancer
Unmet Need: Highly Effective and Selective Drug Delivery Methods for Advanced-Stage Prostate Cancer Treatment Prostate cancer is the second leading cause of cancer-related deaths among men in the United States, with advanced cases requiring urgent treatment. Current therapies offer only limited survival benefits, and many chemotherapies cause severe...
Published: 1/27/2025   |   Inventor(s): Anjali Sharma, Clifford Berkman
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry
Deactivation-free Electrochemical Oxygen Evolution Activity of Topological Weyl Semimetal Co3In2S2
Unmet Need: Necessity of robust and efficient electrochemical oxygen evolution reaction for sustainable energy solution Sustainable oxygen production for medical and industrial applications is one of the prime aims of modern civilization. WSU researchers found an efficient and surprising electrochemical performance of Weyl semimetal Co3In2S2 in its...
Published: 12/4/2024   |   Inventor(s): Jeffrey Bell, Anjaiah Sheelam
Keywords(s): Catalysis for Energy, Catalyst, oxygen evolution reaction
Category(s): Technologies > Health & Well-being > Chemistry
Targeted Drug Delivery Solutions for Advanced Prostate Cancer
Unmet Need: Highly Effective and Selective Drug Delivery Methods for Advanced-Stage Prostate Cancer Treatment Prostate cancer is the second leading cause of cancer-related deaths among men in the United States, with advanced cases requiring urgent treatment. Current therapies offer only limited survival benefits, and many chemotherapies cause severe...
Published: 10/30/2024   |   Inventor(s): Anjali Sharma, Clifford Berkman
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry
High-performance planar solar concentrators based on TiO2 nanoparticle doping
AbstractResearchers at WSU have invented a new conceptual solar concentrator: the light scattering-based solar concentrator (LSSC). This invention is a great enhancement of the photovoltaic (PV) application. Luminescence solar concentrator (LSC), has been considered a viable option to harvest solar energy with minimal environmental impacts. However,...
Published: 10/8/2024   |   Inventor(s): Wenji Dong, Yilin Li
Keywords(s):  
Category(s): Technologies > Energy & Environment > Clean Tech, Technologies > Health & Well-being > Chemistry, Technologies > Next Generation Materials & Technology > Advanced Materials
Molecular Treatment of Succinic Semialdehyde Dehydrogenase Deficiency with Messenger RNA
Unmet Need: Addressing the Imperative of Succinic Semialdehyde Dehydrogenase Deficiency Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare metabolic disorder caused by mutations in the ALDH5A1 gene. The enzyme plays a crucial role in the breakdown of gamma-aminobutyric acid (GABA). WSU Inventors used ALDH5A1-coding mRNA treatment method...
Published: 1/13/2025   |   Inventor(s): Jean-Baptiste Roullet, K. Michael Gibson, Pranav Nawani
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry
Hydrogen Sulfide Releasing Agents
Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 10/8/2024   |   Inventor(s): Ming Xian, Hua Wang, Yu Zhao
Keywords(s): Chemistry
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical
Improved performance of epoxies
Unmet Need: Use of renewable and nontoxic feedstock for epoxiesCurrently over 90% of commercial epoxy resins are derived from the non-renewable petrochemical bisphenol A (BPA). However, BPA is considered as a suspicious endocrine disrupting chemical and may cause harm to human health. In the recent decade, a variety of biobased epoxies have been developed...
Published: 10/8/2024   |   Inventor(s): Jinwen Zhang, Tuan Liu
Keywords(s): bioepoxy, hyperbranched polymer, vegetable oil-based epoxy
Category(s): Technologies > Energy & Environment > Bioproducts, Technologies > Energy & Environment > Clean Tech, Technologies > Health & Well-being > Chemistry
Enhancing Soil Carbon Sequestration to Address Climate Change and Crop Sustainability Concerns
­Unmet Need: Natural Rates of Soil Carbon Sequestration are Insufficient to Address Global Climate Change Concerns and Crop Sustainability Mineral associated carbon is both the most persistent and abundant form of carbon in the global soil carbon pool, estimated at more than 1200 Pg. Despite these large natural mineral associated soil carbon stores...
Published: 10/8/2024   |   Inventor(s): Marc Kramer
Keywords(s): Adsorption, Agriculture, Carbon, Climate Change and Variability, Farming and Ranching, Soil to Society
Category(s): Technologies > Next Generation Materials & Technology > Additive Manufacturing, Technologies > Health & Well-being > Chemistry, Technologies > Energy & Environment > Bioproducts, Technologies > Energy & Environment > Clean Tech, Technologies > Energy & Environment > Instrumentation/Equipment
A Facile, Mild, Fast, Catalyst Free Polylactic Acid (PLA) Degradation Method that Generates a Variety of Valuable Products
­Unmet Need: Current Polylactic Acid Recycling Processes are not Optimal, Requiring High Pressures/Temperatures, Long Degradation Times and/or Catalysts Currently, PLA degradation routes are divided into three categories: high temperature hydrolysis, low temperature hydrolysis and alcoholysis. Alcoholysis usually requires transesterification catalysts...
Published: 10/8/2024   |   Inventor(s): Jinwen Zhang, Yu-Chung Chang, Lin Shao
Keywords(s): 3D printing, aminolysis, chemcial recycling, polylactic acid, recycling of composites
Category(s): Technologies > Energy & Environment > Clean Tech, Technologies > Energy & Environment > Sustainable resources, Technologies > Health & Well-being > Chemistry
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