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Molecular Treatment of Succinic Semialdehyde Dehydrogenase Deficiency with Messenger RNA
Unmet Need: Addressing the Imperative of Succinic Semialdehyde Dehydrogenase Deficiency Succinic semialdehyde dehydrogenase deficiency (SSADHD) is a rare metabolic disorder caused by mutations in the ALDH5A1 gene. The enzyme plays a crucial role in the breakdown of gamma-aminobutyric acid (GABA). WSU Inventors used ALDH5A1-coding mRNA treatment method...
Published: 6/13/2024   |   Inventor(s): Jean-Baptiste Roullet, K. Michael Gibson, Pranav Nawani
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry
Hydrogen Sulfide Releasing Agents
Abstract Hydrogen sulfide (H2S) has demonstrated several essential critical care benefits when delivered properly in low doses. The current state of the art delivery systems rely on gaseous delivery of H2S to patients. WSU researchers have developed chemical agents that controllably decompose to release H2S and demonstrated their efficacy in biological...
Published: 8/22/2024   |   Inventor(s): Ming Xian, Hua Wang, Yu Zhao
Keywords(s): Chemistry
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Health & Well-being > Pharmaceutical
Improved performance of epoxies
Unmet Need: Use of renewable and nontoxic feedstock for epoxiesCurrently over 90% of commercial epoxy resins are derived from the non-renewable petrochemical bisphenol A (BPA). However, BPA is considered as a suspicious endocrine disrupting chemical and may cause harm to human health. In the recent decade, a variety of biobased epoxies have been developed...
Published: 5/25/2023   |   Inventor(s): Jinwen Zhang, Tuan Liu
Keywords(s): bioepoxy, hyperbranched polymer, vegetable oil-based epoxy
Category(s): Technologies > Energy & Environment > Bioproducts, Technologies > Energy & Environment > Clean Tech, Technologies > Health & Well-being > Chemistry
Enhancing Soil Carbon Sequestration to Address Climate Change and Crop Sustainability Concerns
­Unmet Need: Natural Rates of Soil Carbon Sequestration are Insufficient to Address Global Climate Change Concerns and Crop Sustainability Mineral associated carbon is both the most persistent and abundant form of carbon in the global soil carbon pool, estimated at more than 1200 Pg. Despite these large natural mineral associated soil carbon stores...
Published: 5/25/2023   |   Inventor(s): Marc Kramer
Keywords(s): Adsorption, Agriculture, Carbon, Climate Change and Variability, Farming and Ranching, Soil to Society
Category(s): Technologies > Next Generation Materials & Technology > Additive Manufacturing, Technologies > Health & Well-being > Chemistry, Technologies > Energy & Environment > Bioproducts, Technologies > Energy & Environment > Clean Tech, Technologies > Energy & Environment > Instrumentation/Equipment
A Facile, Mild, Fast, Catalyst Free Polylactic Acid (PLA) Degradation Method that Generates a Variety of Valuable Products
­Unmet Need: Current Polylactic Acid Recycling Processes are not Optimal, Requiring High Pressures/Temperatures, Long Degradation Times and/or Catalysts Currently, PLA degradation routes are divided into three categories: high temperature hydrolysis, low temperature hydrolysis and alcoholysis. Alcoholysis usually requires transesterification catalysts...
Published: 5/25/2023   |   Inventor(s): Jinwen Zhang, Yu-Chung Chang, Lin Shao
Keywords(s): 3D printing, aminolysis, chemcial recycling, polylactic acid, recycling of composites
Category(s): Technologies > Energy & Environment > Clean Tech, Technologies > Energy & Environment > Sustainable resources, Technologies > Health & Well-being > Chemistry
Tailored, Non-linear Signal Modulation for Encoding Information in Multiple Dimensions
Unmet Need: Fast, multidimensional analysis of the physical, chemical, and mechanical properties of gas-phase ions, molecules, and particles When coupling two or more stages of on-line or off-line analysis, the second stage of analysis must be much faster than the first to adequately sample information transmitted between dimensions. When the second...
Published: 5/25/2023   |   Inventor(s): Brian Clowers, Elvin Cabrera, David Russell, Arthur Laganowsky
Keywords(s): Ion Mobility Spectrometry, Mass Spectrometry, Signal Processing
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Energy & Environment > Instrumentation/Equipment
High-performance planar solar concentrators based on TiO2 nanoparticle doping
AbstractResearchers at WSU have invented a new conceptual solar concentrator: the light scattering-based solar concentrator (LSSC). This invention is a great enhancement of the photovoltaic (PV) application. Luminescence solar concentrator (LSC), has been considered a viable option to harvest solar energy with minimal environmental impacts. However,...
Published: 4/28/2023   |   Inventor(s): Wenji Dong, Yilin Li
Keywords(s):  
Category(s): Technologies > Energy & Environment > Clean Tech, Technologies > Health & Well-being > Chemistry, Technologies > Next Generation Materials & Technology > Advanced Materials
Environmentally Friendly Method for Recycling Plastic Waste
Unmet Need: Easy recycling of difficult to discard plastics Extensive use of plastics has led to waste disposal management difficulties and serious environmental problems such as intensive energy consumption, toxic gas emission, and occupying many landfills as synthetic plastics such as polyethylene terephthalate (PET) do not rust and are not easily...
Published: 5/25/2023   |   Inventor(s): Jinwen Zhang
Keywords(s): Carbon Dioxide, chemical recycling, Human Impacts and environmental change, Waste plastics
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Energy & Environment > Clean Tech
Low Cost and High Performance Transition-Metal-Based Electrocatalysts for Water Splitting
Unmet Need : Accommodating the unpredictable and intermittent nature of renewable energy requires efficient energy storage and conversion devices. One of the most promising solutions is to convert renewably generated electricity into fuels, such as hydrogen, methane, and ethanol. Electrolysis of water is considered an easy and clean method to obtain...
Published: 6/27/2022   |   Inventor(s): Yuehe Lin, Chengzhou Zhu, Shaofang Fu, Dan Du
Keywords(s): amorphous catalyst, NiFe alloys, oxygen evolution reaction, porous nanostructures, Water Splitting
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Next Generation Materials & Technology > Nanotechnology
Cost-Effective Single-Step Process for the Catalytic Conversion of Methane to Methanol/Formaldehyde
Unmet Need: Currently there is no technology available in the market capable of producing Dimethyl Ether (DME) from methane in a single reactor. DME is an attractive substitute for diesel due to its high cetane number, which is a measure of its ignitibility in compression ignition engines. In addition, DME’s quiet combustion and inability to form...
Published: 5/25/2023   |   Inventor(s): Su Ha, M Norton, Oscar Marin Flores
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Energy & Environment > Energy
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