A Flexible Multiplexed Amplifier for Multichannel Wearable Biopotential Devices

A compact, multiplexed amplifier architecture for wearable biopotential devices, enabling efficient, multi-channel data processing in a miniaturized, flexible format.

Background:

High-density biopotential measurement devices, such as EMGs and EEGs, typically require large and cumbersome amplifiers, limiting their applicability in wearable technologies. This new technology addresses these challenges by miniaturizing multichannel biopotential amplifiers through a multiplexed architecture. This breakthrough enables lightweight, portable devices for applications in human performance assessment, medical diagnostics, and therapeutic interventions.

Technology Overview:

The multiplexed biopotential amplifier developed at University at Buffalo consolidates N channels of data into a single stacked stream using a high-frequency multiplexer. This reduces the hardware footprint by eliminating the need for parallel amplification circuits for each channel. The streamlined architecture integrates a single bioinstrumentation amplifier, enabling flexible, stick-to-skin or clothing-integrated designs. The prototype achieves significant size reduction (0.3 x 4 x 6 cm compared to traditional 5.1 x 15.9 x 22.9 cm systems), lower manufacturing costs, and reduced signal noise, making it ideal for wearable applications.

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romaset, https://stock.adobe.com/uk/455070045, stock.adobe.com

Advantages:

  • Miniaturization allows for flexible, portable, and adhesive wearability.
  • Cost-efficient production by reducing electronic components.
  • Enhanced usability in diverse environments, including sports performance, rehabilitation, and space exploration.
  • Potential for integration into flexible printed circuit boards for seamless application.

Applications:

  • Muscle performance analysis for athletes
  • Neuromuscular rehabilitation and progress tracking
  • Personalized therapeutics and post-stroke monitoring
  • Functional assessments for occupational safety and astronaut recovery
  • Research into neuroplasticity and task performance

Intellectual Property Summary:

Provisional patent application 63/795,749 filed April 28, 2025.

Stage of Development:

TRL 6

Licensing Status:

Available for licensing or collaboration.

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Patent Information: