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Alpha Assay to Screen for Inhibitor Protein-Glycan Interactions in Neurodegeneration
RPI ID: 2024-030-201 Innovation Summary: This technology introduces a bead-based assay platform designed to screen for inhibitors of protein-glycan interactions implicated in neurodegenerative diseases. The assay utilizes functionalized beads to capture glycan-binding proteins and assess their interaction dynamics in the presence of candidate inhibitors....
Published: 3/10/2026
|
Inventor(s):
Chunyu Wang
,
Shannon Faris
Keywords(s):
AlphaScreen
,
Alzheimer's disease
,
Drug Discovery
,
heparan sulfate proteoglycan (HSPG)
,
Heparin
,
tau
,
tau
opathies
Category(s):
Biotechnology and the Life Sciences