Search Results - srinath+kasturirangan

2 Results Sort By:
Antibody based reagents that specifically recognize toxic oligomeric forms of beta-amyloid
Neurodegenerative diseases such as Alzheimer’s are affecting an increasing number, with annual new diagnoses approaching one-half million; and total cost, $150 billion. Early diagnosis and treatment are important for optimal outcomes, yet there is currently no test to detect such diseases in their early, asymptomatic stages. Active immuniza-tion...
Published: 8/27/2025   |   Inventor(s): Michael Sierks, Srinath Kasturirangan
Keywords(s): Bio-Technology, Therapeutics
Category(s): Life Science (All LS Techs), Diagnostic Assays/Devices, Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors
Bi-specific Antibodies as a Therapeutic for Alzheimer’s Disease
Alzheimer’s disease (AD) is one of the most prominent and feared neurodegenerative diseases associated with aging. A hallmark of this disease is the formation of extra-cellular amyloid plaques in the brain. The principle component of these extracellular plaques is amyloid-ß protein (Aß). Though the mechanisms underlying Alzheimer’s...
Published: 2/13/2025   |   Inventor(s): Michael Sierks, Shanta Boddapati, Srinath Kasturirangan
Keywords(s): Bio-Technology, Therapeutics
Category(s): Life Science (All LS Techs), Neurodegenerative Disease Technologies, Non-Cancer Therapeutics, Pharmaceuticals