Search Results - pablo+arce

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Reducing Oxidative Stress with Multifunctional Radical Quenchers
Mitochondria are intracellular organelles responsible for a number of metabolic transformations and regulatory functions. They produce much of the ATP employed by eukaryotic cells. They are also the major source of free radicals and reactive oxygen species that cause oxidative stress. Mitochondrial defects are damaging, particularly to neural and...
Published: 1/25/2024   |   Inventor(s): Sidney Hecht, Jeffrey Armstrong, Omar Khdour, Jun Lu, Pablo Arce
Keywords(s): Therapeutics
Category(s): Life Science (All LS Techs), Pharmaceuticals, Non-Cancer Therapeutics
Silstatins 1-8 and Structural Modifications: Antineoplastic Agents
The promise of marine derived microorganisms as productive sources of new anticancer and antiproliferative drugs continues to expand. Previously, Dr. Pettit and his team isolated and determined the structures of two very potent cancer cell growth inhibitors, cyclodepsipeptides from Bacillus silvestris, carried by a South Pacific crab. Subsequently,...
Published: 2/23/2023   |   Inventor(s): George (Bob) Pettit, Pablo Arce, Robin Pettit
Keywords(s):  
Category(s): Cancer Therapeutics, Life Science (All LS Techs), Pharmaceuticals