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ID
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Anticancer IgG Against Multiple Epitopes on Live Tumors Upon Disruption of ‘Self’ Signaling by CD47
A method to combine two or three mo
no
clonal antibodies (mABs) into one treatment to successfully bind to multiple cancer cell surface epitopes and promote targeted degradation by phagocytosis. Problem: Phagocytosis of ‘self’ cells is generally inhibited by a key macrophage checkpoint interaction between SIRPα on the macrophage and...
Published: 12/15/2025
|
Inventor(s):
Dennis Discher
,
Jason Andrechak
,
Lawrence Dooling
Keywords(s):
Antibody
,
Bioengineering
,
Cell Therapy
,
Drug Target
,
Immu
no
logy
,
Immu
no
ncology
,
Immu
no
therapy
,
Oncology
,
Platform Tech
no
logy
Category(s):
Tech
no
logy Classifications > Therapeutics
Commercially Scalable Quantum Internet Architecture
A hybrid photonic system that enables quantum networking to scale across existing fiber infrastructure. Problem: Developing a commercially scalable quantum internet—one that can substantially reduce deployment costs by using existing fiber networks—is challenged by the fact that current quantum systems remain isolated laboratory platforms...
Published: 12/15/2025
|
Inventor(s):
Liang Feng
,
Yichi Zhang
,
Robert Broberg
,
Jonathan Smith
Keywords(s):
Electronic Materials
,
Optics & Photonics
Category(s):
Tech
no
logy Classifications > Computer Information Systems
,
Tech
no
logy Classifications > Hardware & Components
,
Tech
no
logy Classifications > Materials
Hardware-Software Solution for Using Patented FDT System in Small Planes
This tech
no
logy enables small aircraft to collect, process, and transmit flight data in real time to the cloud using affordable hardware and software, improving crash investigation and safety monitoring without needing complex avionics systems. Background: In the field of aviation safety and accident investigation, the collection and analysis of...
Published: 12/15/2025
|
Inventor(s):
Junaid Zubairi
Keywords(s):
analytics
,
data collection
,
Tech
no
logies
Category(s):
Campus > SUNY Fredonia
,
Tech
no
logy Classifications
,
Tech
no
logy Classifications > Instrumentation
Energy Performance Prediction Model for Hurricane-Damaged Building Envelopes
Provides Building Energy Performance Access by Connecting Structural Engineering and Energy Efficiency in Five Interconnected Analyses This five-stage analysis system predicts energy consumption in buildings following a natural hazard based on wind-induced damage to their building envelopes from the hazard. Buildings account for approximately 40% of...
Published: 12/12/2025
|
Inventor(s):
Ryan Sharston
,
Arthriya Subgra
no
n
,
Imad Alhayik
Keywords(s):
Category(s):
Tech
no
logy Classifications > Engineering > Civil
Ultra-Sensitive Wireless Capacitive Na
no
composite-Based Pressure Sensors
Invention Description Wireless capacitive pressure sensors have been widely studied for health monitoring applications including continues monitoring of blood flow in patients suffering from high blood pressure, tracking of bladder pressure in patients with urine incontinence, and monitoring intracranial pressure in patients experiencing traumatic...
Published: 12/12/2025
|
Inventor(s):
Layla Khalifehzadeh
,
Hamed Arami
,
Seyedamin Hashemi
,
Saman Ebrahimibasabi
,
Mostafa Sajjadi
Keywords(s):
Category(s):
Wearable
,
Medical Diag
no
stics/Sensors
,
Medical Devices
,
Physical Science
,
Advanced Materials/Na
no
technology
No
vel Therapy for Ischemic and Pressure-Overload Heart Diseases
This
no
vel therapy involves using valosin-containing protein (VCP) to prevent or treat ischemic and pressure overload-induced heart disease. Inactivation and reduced VCP expression are highly associated with multiple cardiac diseases. Overexpression of VCP in the heart has been found to reduce infarct size during ischemia-reperfusion injury and also...
Published: 12/12/2025
|
Inventor(s):
Hongyu Qiu
Keywords(s):
Category(s):
Tech
no
logy Classifications > Healthcare Portfolios > Heart and Vascular
,
Tech
no
logy Classifications > Life Sciences > Biologics
,
Tech
no
logy Classifications > Life Sciences > Therapeutics
Digital Vivarium – RFID Census Database and Scanning Application
RFID scanner with application on screen Invention Summary: Traditional research animal census methods rely on manual counts or generic inventory tools that are error-prone, inefficient, and
no
t designed for cage-level tracking. Existing RFID systems from other industries are often too complex or poorly suited for animal facility workflows....
Published: 12/11/2025
|
Inventor(s):
Matthew Keller
,
James Boyce
,
Alexander Lee
,
Matthew Tallman
Keywords(s):
Category(s):
Tech
no
logy Classifications > Animal Health & Care
,
Tech
no
logy Classifications > Software & Algorithms
,
Tech
no
logy Classifications > Software & Copyright
Fluorescently Labeled INtracellular Ge
no
mics (FLING) and Fluorescent In Situ Amplified (FISA)
Invention Description Accurately identifying and sequencing rare ge
no
types within complex cell populations remains a major challenge across biological research. Conventional sequencing approaches often require large amounts of high-quality DNA, struggle with heterogeneous or degraded samples, and fail to retain the spatial or cellular context necessary...
Published: 12/11/2025
|
Inventor(s):
Kerry Geiler-Samerotte
,
Leandra Brettner
,
Parker Crossland
,
Kara Schmidlin
Keywords(s):
Category(s):
Bioanalytical Assays, Chemistries & Devices
,
Chemical/Biological Sensors
,
Diag
no
stic Assays/Devices
,
Ge
no
mic Assays/Reagents/Tools
,
Life Science (All LS Techs)
,
Imaging
Enhanced Mutual Coupling Calibration (EMC²) for Built-in Self-Testing in Large Antenna Arrays
Invention Description Antennas are essential to multiple systems, such as mobile communications and military and civilian radars, security screening, imaging, mapping, localization, and much more. With the increased demand for accurate and optimal performance of such systems, it is critical to have precise k
no
wledge of transmitted/received signals,...
Published: 12/11/2025
|
Inventor(s):
Mohammed Aladsani
,
Georgios Trichopoulos
,
Sule Ozev
,
Ferhat Can Ataman
,
Chethan Kumar Y.B.
Keywords(s):
Category(s):
Wireless & Networking
,
Physical Science
,
Intelligence & Security
Multi-Level Scheduling and Partitioning of Reconfigurable Processor Arrays (Case
No
. 2026-011) Circular Elevator Style Network-on-Chip (Case No. 2026-012) and Pattern Compilation for Runtime Reconfigurable Arrays (Case No. 2026-013)
Summary: UCLA researchers in the Department of Electrical and Computer Engineering have developed a high-speed runtime reconfigurable processor array (RTRA) that enables on-chip scheduling and rapid multi-program execution with unprecedented energy and area efficiency for dynamic computing workloads. Background: Dynamic digital signal processing...
Published: 12/11/2025
|
Inventor(s):
Dejan Markovic
,
Hong Seok Lee
,
Chenkai Ling
Keywords(s):
computational efficiency
,
computational efficiency and analysis
,
edge computing
,
energy-efficient
,
Hardware
,
high speed
,
large-area arrays
,
low latency computing
,
low-power architecture
,
Microarray
,
Microprocessor
,
processor design
,
programming
,
scalable manufacturing
,
System On A Chip
Category(s):
Electrical > Signal Processing
,
Electrical
,
Electrical > Electronics & Semiconductors
,
Software & Algorithms
,
Electrical > Computing Hardware
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