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Method of Treating Obesity-Induced Glucose Intolerance and Liver Fibrosis (UCLA Case
No
. 2021-323)
UCLA researchers in the School of Engineering have discovered a
no
vel method to treat obesity-induced glucose intolerance and liver fibrosis. BACKGROUND: The CDC reports that 41.9% of adults ages 20 and over are obese. An increased incidence of obesity also increases the rates of comorbidities such at type 2 diabetes mellitus (T2DM), non-alcoholic...
Published: 9/24/2024
|
Inventor(s):
Zhen Gu
Keywords(s):
glucose intolerance
,
liver fibrosis
,
Na
no
particles
,
No
tch signaling pathway
,
obesity
Category(s):
Therapeutics > Metabolism And Endocri
no
logy
SELECTIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES
SELECTIVE SENSITIZATION OF CANCER CELLS TO ELIMINATION BY CYTOTOXIC LYMPHOCYTES Researchers at Stanford University have developed a
no
vel method for the treatment and prevention of cancer. The immune system is an integral part of the human body’s response to outside threats, including cancer. Specifically, cytotoxic CD8+ T cells have been...
Published: 9/24/2024
|
Inventor(s):
Reece Akana
Keywords(s):
Cancer
,
Immu
no
-Oncology
,
T-Cell Activation
Category(s):
Tech
no
logy Classifications > Biology
COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS
COMPOSITIONS AND METHODS FOR RE-ACTIVATION OF DYSFUNCTIONAL SKELETAL STEM CELLS Researchers at Stanford University have developed a
no
vel therapeutic avenue for the treatment of osteoporosis and other musculoskeletal diseases. Musculoskeletal disease incidence rates have increased in recent years in response to an aging population. Available...
Published: 9/24/2024
|
Inventor(s):
Charles Chan
,
Thomas Ambrosi
,
Irving Weissman
,
Michael Longaker
,
Rahul Sinha
,
Debashis Sahoo
Keywords(s):
Hydrogel
,
Stem Cell
Category(s):
Tech
no
logy Classifications > Biology
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION
DESIGN OF UNIVERSAL H5 INFLUENZA VIRUS VACCINE CANDIDATES VIA ANTIGEN REORIENTATION Researchers at Stanford University have developed
no
vel universal vaccine candidates for H5 influenza viruses. Influenza remains a serious threat to public health. H5 avian influenza strains are among the most concerning despite lack of documented human to human...
Published: 9/24/2024
|
Inventor(s):
Duo Xu
,
Peter Kim
Keywords(s):
Immu
no
focusing
,
Vaccine
Category(s):
Tech
no
logy Classifications > Biology
NO
VEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR
NO
VEL SMALL MOLECULE NEGATIVE ALLOSTERIC MODULATORS OF THE MU-OPIOD RECEPTOR Researchers at Stanford University and Washington University have discovered a novel molecular pathway for the treatment of opioid overdose. Opioids are a powerful tool for pain management when used in clinical care settings. However, in recent years these drugs have...
Published: 9/24/2024
|
Inventor(s):
Evan Obrien
,
Kaavya Kumar
,
Brian Kobilka
,
Susruta Majumdar
,
Vipin Rangari
Keywords(s):
Opiod
,
Pain
Category(s):
Tech
no
logy Classifications > Chemistry
C41 Analogs
This invention relates generally to neurodegenerative diseases and conditions, such as Alzheimer’s Disease, characterized with dysfunctional energetic function, unregulated microglia phagocytic activity and other related de-regulated biological functions. This invention further relates to methods and compositions for treating such neurodegenerative...
Published: 9/24/2024
|
Inventor(s):
Wei Wang
,
Rui Chang
,
Vijayan Ramachandran
,
Patrick Ronaldson
Keywords(s):
Category(s):
Tech
no
logy Classifications > Healthcare Portfolios > Neurology
,
Tech
no
logy Classifications > Life Sciences > Nutraceuticals
,
Tech
no
logy Classifications > Life Sciences > Small Molecules
,
Tech
no
logy Classifications > Life Sciences > Therapeutics
,
Tech
no
logy Classifications > Life Sciences > Biologics
Stimulation Device to treat Hand Weakness from Stroke or Spinal Injury
A growing number of people experience hand weakness due to stroke or spinal cord injuries. Electrical stimulation (e-stim) devices are commonly used to assist in hand weakness therapy. However, they are bulky, expensive, uncomfortable (may be ill-fitting, cause skin irritation or unpleasant sensation), and
no
n-portable, eliminating the potential for...
Published: 9/24/2024
|
Inventor(s):
Atharva Wani
,
Niteesh Nigam
,
Onkar Chavan
,
Yash Bellap
,
Joelly Lobato
,
Ishan Swanand Vyas
,
Suhrud Parag Joglekar
Keywords(s):
Category(s):
Life Science (All LS Techs)
,
Medical Devices
,
Manufacturing/Construction/Mechanical
Vital Signs Monitoring using Depth Cameras
Cardiovascular disease is responsible for an estimated 17.9 million deaths each year, making it the leading cause of death worldwide. Continuous heart health monitoring way is the best preventative for heart failure. However, standard monitoring devices, including ECG and PPG, require direct physical contact, which can be difficult for certain patient...
Published: 9/24/2024
|
Inventor(s):
Yu Rong
,
Daniel Bliss
Keywords(s):
Category(s):
Computing & Information Tech
no
logy
,
Medical Devices
,
Life Science (All LS Techs)
,
Medical Diag
no
stics/Sensors
,
Medical Imaging
Head Motion Correction with Soft Pressure Pad for MRI Scans
Addressed Need Head motion remains a major challenge during medical imaging scans, particularly in pediatric and older patient populations. Motion impacts diag
no
stic image quality, costing both time and money in the clinical setting. In research, motion artifacts can introduce errors into quantitative measurements, especially in high-resolution or...
Published: 9/24/2024
|
Inventor(s):
Keywords(s):
Category(s):
Medical Devices
,
Medical Imaging
Inhibitors of the N-terminal Domain of the Androgen Receptor (UCLA Case
No
. 2023-075)
Researchers at UCLA under the guidance of Drs. Matthew Rettig and Michael Jung have developed
no
vel molecular compounds that reduce growth of prostate cancer cells. Dr. Jung in collaboration with Dr. Rettig have furthered the development of these compounds by synthesizing a new series of analogues that have similar inhibitory effects. BACKGROUND: Prostate...
Published: 9/23/2024
|
Inventor(s):
Matthew Rettig
,
Michael Jung
Keywords(s):
androgen receptor therapy
,
castration resistant prostate cancer
,
Oncology
,
Oncology (Small Molecules, Peptides and Antibodies)
,
prostate cancer
,
small molecules
Category(s):
Therapeutics > Oncology
,
Therapeutics > Oncology > Oncology (Small Molecules)
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2
3
4
5
6
7
8
9
10
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