Search Results - mark+anderson

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PERILIPIN-1 SPECIFIC T CELLS FOR SELECTIVE FAT TARGETING
Researchers at UCSF and CZ Biohub SF have described cells expressing a heterologous T-cell receptor, that binds to an adipose-specific protein perilipin 1 peptide complex, thereby enabling selecting targeting of fat cells. T cell tolerance is enforced in the thymus through the expression of a wide array of self proteins called tissue-specific antigens...
Published: 10/23/2025   |   Inventor(s): Mark Anderson, Irina Proekt, Joseph DeRisi
Keywords(s): Autoantibody, Autoimmune, Therapeutic
Category(s): Technology Classifications > Biology
­AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY
­AUTOANTIBODIES AS BIOMARKERS FOR LIPODYSTROPHY Researchers at UCSF and the Chan Zuckerberg Biohub have developed methods to identify a subject that is at risk of developing autoimmune-related lipodystrophy. Lipodystrophy is a clinical phenotype defined by a reduction in subcutaneous fat or adipose tissue. Excessive fat loss can lead to an imbalance...
Published: 12/5/2024   |   Inventor(s): Caleigh Mandel-Brehm, Joseph DeRisi, Mark Anderson
Keywords(s): Antibody, Autoantibody, Autoimmune, Biomolecules, Diagnosis, IgG, Immunotherapy, Lipodystrophy
Category(s): Technology Classifications > Biology
AUTOANTIBODIES AS BIOMARKERS FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1
AUTOANTIBODIES AS BIOMARKERS FOR AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1 Researchers at UCSF and the Chan Zuckerberg Biohub have identified multiple common autoantibody targets in APS1 patients through proteome-wide programmable phage-display. The identification of autoantigens remains a critical challenge for understanding and treating autoimmune...
Published: 10/26/2024   |   Inventor(s): Sara Vazquez, Mark Anderson, Joseph DeRisi
Keywords(s): Antibody, Autoantibody, Diagnosis, Particle Display, Serum
Category(s): Technology Classifications > Biology