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Search Results - lin-kun+an
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DNA Methylation-Based Algorithm to Diagnose Irritable Bowel Syndrome and Other GI Conditions (UCLA Case No. 2022-229)
UCLA researchers in the Department of Gastroenterology have developed a DNA methylation-based algorithm to diagnose irritable bowel syndrome and other GI conditions. Blood-based genome-wide DNA methylation profiles have been utilized to develop a reliable test to diagnose irritable bowel syndrome (IBS) versus inflammatory bowel disease (IBD), celiac...
Published: 9/11/2025
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Inventor(s):
Lin Chang
,
Swapna Joshi
Keywords(s):
Category(s):
Therapeutics > Gastroenterology
,
Platforms > Diagnostic Platform Technologies
AUTOMATED STRUCTURAL DAMAGE DETECTION AND LOCALIZATION USING MECHANICS-INFORMED DATA ANALYSIS
VAlue proposition Structural health monitoring ensures the safety and longevity of structures like buildings and bridges. As the volume and scale of structures and the impact of their failure continue to grow, there is a need for techniques that are scalable, inexpensive, can operate passively without human intervention, and are customized for each...
Published: 8/19/2025
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Inventor(s):
Vishnu Boddeti
,
Nizar Lajnef
,
Li Xuyang
,
Mahdi Masmoudi
Keywords(s):
Category(s):
Test and Measurement
Efficient Deep-Blue LEDs Based on Hybrid Copper Iodide Emissive Layer
Components of a blue LED incorporating hybrid Cul emissive layer Invention Summary: Blue light emitting diodes (LEDs) are essential to energy-efficient lighting technologies, especially for the creation of white light. However, deep blue emitting cadmium-based quantum dots and lead-based perovskites pose toxicity and environmental concerns...
Published: 8/20/2025
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Inventor(s):
Jing Li
,
Kun Zhu
Keywords(s):
Electronics
,
LEDs
,
Photonics and photovoltaics
Category(s):
Technology Classifications > Electronics/Semiconductor
,
Technology Classifications > Physical Sciences & Engineering
Chemically Modified AMPA Receptor RNA Aptamers Designed for In Vivo Use
" RNA aptamers as glutamate agonists offer potential therapeutics for a range of neurological disorders RSS.HDBackground> Background: < Neurological disorders are increasingly recognized as major causes of death and disability worldwide. Nearly 500,000 cases of brain tumor, multiple sclerosis, and amyotrophic lateral sclerosis (ALS) are...
Published: 5/13/2025
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Inventor(s):
Li Niu
,
Zhen Huang
Keywords(s):
Technologies
Category(s):
Technology Classifications > Screens and Assays
,
Technology Classifications > Research Tools and Reagents
,
Campus
,
Campus > University at Albany
Potent and Selective Inhibition of a Single AMPA Receptor Subunit by an RNA Aptamer
Inhibitors of AMPA type glutamate ion channels for the treatment of neurological disorders such as ALS, Alzheimer's, and Parkinson's. Background: Ionotropic glutamate receptors (iGluRs) play special roles in brain activities, such as memory and learning, and have been implicated in a variety of neurological diseases, such as post-stroke cellular...
Published: 5/13/2025
|
Inventor(s):
Li Niu
,
Zhen Huang
,
Yan Han
,
Congzhou Wang
,
Jae Seon Park
Keywords(s):
RNA
,
Technologies
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus
,
Campus > University at Albany
Drug Candidate for ALS
RNA aptamers that focus on glutamate receptors are a potential drug candidate for amyotrophic lateral sclerosis (ALS). Background: Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease, is a progressive neuromuscular disease for which there is no cure. The disease attacks motor neurons that run from the brain to the spinal cord...
Published: 5/13/2025
|
Inventor(s):
Li Niu
,
Zhen Huang
Keywords(s):
ALS
,
amyotrophic lateral sclerosis
,
aptamers
,
drug design
,
Lou Gehrig's disease
,
MND
,
motor neurone disease
,
RNA
Category(s):
Technology Classifications > Biomedical Science and Engineering
,
Campus > University at Albany
Method for Vascular Regeneration and Wound Treatment
Asset/Technology Type Therapeutic Strategy Description of Invention The invention is a therapeutic approach for modulating cellular trans-differentiation and potentially angiogenesis by modulating O-glcnacylation (GlcNAc) of proteins, to treat various conditions. The inventors used existing small molecules to prove the concept in vitro and in vivo....
Published: 5/21/2025
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Inventor(s):
John Cooke
,
Li Lai
Keywords(s):
Category(s):
Clinical Area
,
Clinical Area > Cardiovascular
,
Research Area > Heart and Vascular
,
Research Area > Regenerative Medicine
,
Technology Classifications
,
Technology Classifications > Other
Extremely Strong Material Made from Ternary Acrylic Resin System
Title: Extremely Strong Material Made from Ternary Acrylic Resin System Unmet Need: Chemical recycling of plastic waste through aminolysis diverts waste stream to useful resin products Polylactic acid (PLA) is the most used bioplastic in the world. PLA products include disposable cutlery, electronics, and medical implants. Degradation of PLA by aminolysis...
Published: 3/18/2025
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Inventor(s):
Jinwen Zhang
,
Lin Shao
,
Yu-Chung Chang
Keywords(s):
3D printing
,
acrylic resin
,
lactic acid
,
photocuring
,
polylactic acid
,
recycling
Category(s):
Technologies > Energy & Environment > Clean Tech
Prebiotic Treatment for the Prevention of Multiple Oral Diseases
Inhibits Disease-Causing Bacteria and Restores Balance to the Oral Microbiome This prebiotic agent can prevent and treat oral diseases by eliminating disease-causing bacteria, while simultaneously promoting the growth of healthy bacteria. An estimated 3.9 billion people worldwide suffer from oral diseases such as cavities, oral thrush, peri-mucositis...
Published: 1/31/2025
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Inventor(s):
Lin Zeng
,
Fan Ren
,
Jennifer Andrew
,
Jacqueline Abranches
,
Josephine Esquivel-Upshaw
,
Bruna Garcia
,
Luiz Gonzaga
,
Robert Burne
Keywords(s):
Category(s):
Technology Classifications > Human Health Care > Nutraceutical
,
Technology Classifications > Medical Devices > Consumable
Acquisition – Software to Control Acquisition of Images for Near-Earth Object Survey Operations
The Acquisition subsystem in the Catalina Sky Survey (CSS) software suite manages the operation of telescopes and instruments to capture data on asteroids and Near-Earth Objects (NEOs). Once areas of the sky are selected for observation, Acquisition takes over, accepting the input from the Planner subsystem and coordinating the telescope, camera, and...
Published: 12/9/2024
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Inventor(s):
A Departmental Work
Keywords(s):
Category(s):
Technology Classifications > Software & Information Technology > Open Source
,
Technology Classifications > Software & Information Technology
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