Search Results - life+sciences+%3e+diagnostic

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Cytokine analysis for seronegative autoimmune epilepsy diagnosis

This study found a unique profile of 14 elevated cytokines, potential biomarkers, in patients with a specific type of epilepsy (snAAE) that doesn’t respond to traditional antibody tests. Background Autoimmune-associated epilepsy (AAE) is a significant contributor to drug-resistant epilepsy cases, characterized by a positive response to...

Published: 11/18/2024 | Inventor(s): Esther Melamed, Cole Maguire, Katherine Motovilov, Deborah Briggs

Keywords(s):

Category(s): Life sciences > Diagnostic

Wearable tongue tracker for silent speech interfaces

MagTrack is a lightweight, wearable device that utilizes magnetic fields to track tongue movements, enabling silent speech recognition and other applications like speech therapy. Background Silent speech interfaces (SSIs) aim to restore communication for individuals who have lost their voice but retain the ability to articulate, such as those who...

Published: 10/23/2024 | Inventor(s): Jun Wang, Beiming Cao

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Category(s): Life sciences > Diagnostic, Life sciences > Imaging

Computing system for cognitive impairment detection

This computing system can detect cognitive impairment. It presents memory and verbal tasks, analyzes user input, and provides care recommendations. Background Digital healthcare solutions are being intensely studied for rapid identification and effective management of patients with Alzheimer’s disease and related disorders (ADRD). Early detection...

Published: 10/23/2024 | Inventor(s): Robin Hilsabeck, Jeffrey Keller, Maya Henry, Paul Toprac, Paul Rathouz, Junyi Li, Ray Allen

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Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic

Kinematic data analysis for stress detection

This technology uses movement data from laparoscopic instruments to detect stress levels in surgeons in near real-time. An AI model analyzes the data, identifying movement patterns associated with stress, and can be integrated into robotic surgical platforms for feedback and guidance. Background Laparoscopic surgery is a complex and demanding field...

Published: 10/23/2024 | Inventor(s): Ann Majewicz Fey, Yi Zheng

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Category(s): Life sciences > Diagnostic, Life sciences > Medical technology > TechBio (software innovation in healthcare)

High-throughput RNA sequencing technology for comprehensive transcriptome profiling and biomarker identification in inflammatory breast cancer

The technology utilizes TGIRT-seq, a high-throughput RNA sequencing method, to identify potential biomarkers for inflammatory breast cancer by profiling coding and non-coding RNAs in tumor and blood samples, aiding in diagnosis and disease monitoring. Background Inflammatory breast cancer (IBC) is recognized as the most aggressive form of breast cancer,...

Published: 10/22/2024 | Inventor(s): Alan Lambowitz, Dennis Wylie, Lauren Ehrlich, Elizabeth Kiddie, Hengyi Xu, Jun Yao, Naoto Ueno, Xiaoping Wang

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Category(s): Life sciences > Diagnostic

Harnessing the Type III-Dv CRISPR-Cas system for targeted RNA modification and detection

The Type III-Dv CRISPR-Cas system is a genetic tool designed for precise RNA targeting and cleavage. It uses a complex of Cas proteins to bind and modify single-stranded nucleic acids, enabling applications in gene silencing and RNA detection. Background The field of CRISPR-Cas technology has revolutionized genetic engineering by providing precise...

Published: 10/21/2024 | Inventor(s): David Taylor, Peter Fineran, Robert Fagerlund, Leah Smith, David Mayo-Munoz, Evan Schwartz, Jack Bravo

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Category(s): Life sciences > Diagnostic, Life sciences > Research tools > Reagent

High-throughput detection of single nucleotide polymorphisms (SNPs) via CRISPR-based diagnostic platform

This CRISPR-based technology enables precise detection of single nucleotide polymorphisms (SNPs) in nucleic acids by using programmed mismatches between CRISPR RNA and target nucleic acids, facilitating high-throughput, quantitative, and point-of-care diagnostics. Background Single nucleotide polymorphisms (SNPs) play a crucial role in disease susceptibility,...

Published: 10/21/2024 | Inventor(s): Ilya Finkelstein, Hung-Che Kuo, Chia-Wei Chou

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Category(s): Life sciences > Diagnostic, Life sciences > Research tools

Stabilized coronavirus spike proteins for enhanced vaccine efficacy

Engineered proteins with stabilized coronavirus spike protein ectodomains enhance immune response and are useful in diagnostics, screening, and vaccines against coronaviruses like SARS-CoV-2 by maintaining prefusion conformation, potentially producing cross-reactive antibodies. Background The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has...

Published: 10/21/2024 | Inventor(s): Jason McLellan, Ching-Lin Hsieh

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Category(s): Life sciences > Therapeutics > Vaccines, Life sciences > Diagnostic

Engineered chimeric fusion proteins

Enhancing stability and expression for improved vaccines and diagnostics in hMPV and RSV The invention describes engineered chimeric F proteins combining sequences from human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) to enhance stability and expression. These proteins are useful in vaccines, diagnostics, and antibody screening. Background Respiratory...

Published: 10/16/2024 | Inventor(s): Jason McLellan, Ching-Lin Hsieh

Keywords(s):

Category(s): Life sciences > Therapeutics > Vaccines, Life sciences > Diagnostic

Blood pressure regulation via thermal control during sleep

This technology uses a stimulating device and blood pressure monitor to regulate blood flow and lower blood pressure during sleep through targeted thermal stimulation, promoting cardiovascular health by integrating into a climate-controlled bed. Background High blood pressure, or hypertension, is a significant health concern linked to various cardiovascular...

Published: 10/4/2024 | Inventor(s): Kenneth Diller, Sepideh Khoshnevis, Laura Hemmen Namisnak

Keywords(s):

Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Diagnostic

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