Search Results - life+sciences+%3e+diagnostic

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Functionalized expanded porphyrin technology to detect high-valent actinide cations
Functionalized expanded porphyrins are designed as spectrometric sensors for detecting high-valent actinide cations like uranyl. They can be attached to solid supports, exhibiting a color change upon binding, useful in environmental safety applications. Background The detection of high-valent actinide cations such as uranyl, neptunyl, and plutonyl...
Published: 9/16/2024   |   Inventor(s): Jonathan Sessler, Patricia Melfi
Keywords(s):  
Category(s): Life sciences > Diagnostic, Life sciences > Research tools > Tool/assay/screening platform
Predicting breast cancer response to therapy with MRI and modeling
Background/problem Neoadjuvant therapy (NAT) for cancer treatment is currently based on generalized population-based data such as receptor status, tumor grade, body surface area, and genetic markers. This approach is inherently limited, as it does not account for the unique spatial and physiological characteristics of individual tumors. Consequently,...
Published: 9/9/2024   |   Inventor(s): Thomas Yankeelov, Angela Jarrett, David Hormuth, Anum Kazerouni, Chengyue Wu, Stephanie Barnes
Keywords(s):  
Category(s): Life sciences > Imaging, Life sciences > Diagnostic
Rapid characterization of analytes in saliva
A system rapidly detects analytes in saliva using a light source, sensor array, and detector, with chemically sensitive particles in cavities that signal inter­actions with analytes, characterized through pattern recognition techniques. Background Saliva has garnered significant interest as a diagnostic medium due to its non-invasive collection...
Published: 8/19/2024   |   Inventor(s): John McDevitt, Eric Anslyn, Dean Neikirk, Nicolaos Christodoulides, Jason Shear
Keywords(s):  
Category(s): Life sciences > Diagnostic, Life sciences > Medical technology > Medical devices
3D-printed biosensors for high-sensitivity molecular detection
This invention describes the creation of highly sensitive biosensors through 3D printing using stereolithography (SLA). These biosensors, made from a biopolymer blend with specific monomers and a photoinitiator, are functionalized with recognition molecules to detect small and large analytes, including disease markers, in commercial well plates. Background Additive...
Published: 7/26/2024   |   Inventor(s): Mohammed Maniruzzaman, Yu Zhang
Keywords(s):  
Category(s): Life sciences > Research tools > Tool/assay/screening platform, Life sciences > Diagnostic
Efficient MR fingerprinting using B-splines to improve (quantitative) MRI
Background/problem Magnetic resonance imaging (MRI) is a state-of-the-art diagnostic imaging modality which beneficially features excellent soft tissue contrast and lacks use of ionizing radiation. In clinical practice, MRI generates contrast-weighted images based on the intrinsic tissue parameters of the subject, which are then interpreted by a radiologist....
Published: 5/24/2024   |   Inventor(s): Bo Zhao, Evan Crafts
Keywords(s):  
Category(s): Life sciences > Imaging, Life sciences > Diagnostic
Recognitive hydrogel technology for precise molecular detection
Background The field of chemical sensor technology has long sought methods to accurately detect and measure molecular presence and concentration in various environments. A pervasive challenge has been developing sensors that can selectively recognize specific molecules in complex mixtures. Traditional sensors often struggle with non-specific binding,...
Published: 9/24/2024   |   Inventor(s): Nicholas Peppas, Carolyn Bayer
Keywords(s):  
Category(s): Life sciences > Biomaterials, Life sciences > Diagnostic
Method for detecting antibodies to folic acid
Background Folate, an essential B-vitamin, is crucial for a variety of health-related functions. The recognition that too few women obtained sufficient folate levels from their diet and knowing that a folate deficiency put embryos at risk for serious birth defects led to mandatory fortification of certain foods to prevent deficiencies. Such preventive...
Published: 4/16/2024   |   Inventor(s): Richard Finnell, Robert Cabrera
Keywords(s):  
Category(s): Life sciences > Diagnostic, Life sciences > Immunology
Rapid, multi-targeted, modular virus sensing platform based on graphene field-effect sensing
Background The SARS-CoV-2 pandemic underscored the necessity for rapid and precise detection of viruses that share similar symptoms, leading to a strain on healthcare systems. Identifying specific pathogens such as influenza alongside COVID‑19 is crucial for tailored treatment plans. Technology overview A novel technology based on liquid-gated graphene...
Published: 6/10/2024   |   Inventor(s): Dmitry Kireev, Deji Akinwande, Neelotpala Kumar, Dalton Towers
Keywords(s):  
Category(s): Life sciences > Diagnostic
First-in-class blood-based diagnostic panel for depression and suicide risk
Background The instinct to stay alive and maintain well-being is fundamental to all of us, yet nearly a million lives are lost to suicide each year around the world, presenting a significant public health challenge. Despite ongoing efforts, effectively identifying the risk and preventing suicide remains a complex issue. Biologically, suicide often...
Published: 3/4/2024   |   Inventor(s): Mbemba Jabbi, Dhivya Arasappan, Dennis Wylie
Keywords(s):  
Category(s): Life sciences > Diagnostic, Life sciences > Therapeutics
Knitted strain sensor for pharyngeal rehabilitation
Problem Dysphagia, or swallowing dysfunction, affects 9.5 million people in the United States. Dysphagia poses significant risks including malnutrition, dehydration, aspiration pneumonia, and death. Dysphagia is associated with diseases including stroke, muscular dystrophy, and throat cancer. The impact of dysphagia extends beyond physical discomfort,...
Published: 2/15/2024   |   Inventor(s): Jonathan Chen, James Sulzer, Corinne Jones, David Zhang, Drake Rowland, Wei Li
Keywords(s):  
Category(s): Life sciences > Medical technology > Medical devices, Life sciences > Diagnostic
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