Search Results - justin+halman

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Nucleic Acid Nanoparticles (NANP) and Methods of Using Same for Controlled Immunomodulation
Abstract: The technology is directed to compositions and methods of designing nucleic acid nanoparticles (NANPs) composed entirely of DNA, RNA, or DNA and RNA to achieve desirable immunostimulation and decrease undesirable effects on the immune system by changing the composition of the NANP. Benefits of the invention include the desirable activation...
Published: 4/8/2024   |   Inventor(s): Kirill Afonin, Justin Halman, Marina Dobrovolskaia, Enping Hong
Keywords(s): CANCER, Dobrovolskaia, IMMUNE, Immunomodulation, Inflammation, Nucleic Acid Nanoparticle
Category(s): TherapeuticArea > Oncology, Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Immunology, Application > Therapeutics
Functionally-Interdependent Shape-Switching Nucleic Acid Nanoparticles
Abstract: RNA interference (RNAi) is a naturally occurring post-transcriptional gene regulation process that represses the expression of specific genes. Exploiting endogenous RNAi by externally-delivered small-interfering RNA (siRNA) is a promising therapeutic for the treatment of various diseases representing several major unmet medical needs.  Researchers...
Published: 8/14/2024   |   Inventor(s): Bruce Shapiro, Kirill Afonin, Eckart Bindewald, Mathias Viard, Wojciech Kasprzak, Justin Halman, Marina Dobrovolskaia
Keywords(s): CANCER, Drug Delivery, Molecular imaging, Nanoparticle, RNA interference, RNAi, SiRNA, Small-interfering RNA
Category(s): Collaboration Sought > Licensing, Collaboration Sought > Collaboration, TherapeuticArea > Infectious Disease, Application > Therapeutics, TherapeuticArea > Oncology