Search Results - jianming+liu

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Novel Method to Treat Heart Disease in Duchenne Muscular Dystrophy (DMD) Patients
Advantages: Novel Therapeutic target to treat cardiac dystrophy in DMD: Nox4 Inhibition Potential to reduce fibrosis and improve cardiac function over conventional treatments Potential to combine NOX4 inhibition with dystrophin replacement therapies Summary: Duchenne Muscular Dystrophy (DMD) is a genetic disorder caused by mutations in the...
Published: 4/1/2025   |   Inventor(s): DaZhi Wang, Zhanpeng Huang, Jianming Liu
Keywords(s): Cardiological Diseases Treatment
Category(s): Technology Classifications > Medical > Medical Diagnostics, Technology Classifications > Medical > Therapeutics
DNA Methylation Barriers
In normal differentiated cells, most of the genome is densely methylated, except CpG islands near promoters of actively transcribed genes. Maintaining this boundary between unmethylated promoter-associated and adjacent methylated regions is crucial as loss of segregation can lead to disease. Unfortunately, it is not clear where these boundaries are,...
Published: 2/13/2025   |   Inventor(s): Li Liu, Jingmin Shu
Keywords(s):  
Category(s): Applied Technologies, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Diagnostic Assays/Devices
p300 KO HEK293T Cell Line for Multiple Research Applications
This technology includes p300 KO HEK293T cells using crispr/cas9 mediated gene editing technology to be used for various research applications. We showed that p300 deficient cells have impaired glycolysis and are hypersensitive to glucose depletion-induced cell death. p300 is one of major transcriptional co-activators that regulates gene transcription...
Published: 8/12/2024   |   Inventor(s): Ming Ji, Xiaoling Li
Keywords(s):  
Category(s): Application > Research Materials, ResearchProducts > Human Cell Lines, TherapeuticArea > Neurology
Vapor Deposited and Doped Perovskite Thin Film for LED Applications
Background Perovskites have widely been considered as promising next-generation materials for future display and solid-state lighting applications. Most current perovskite LEDs are produced using solution processing, and over 20% external quantum efficiencies (EQE) in LEDs have been achieved in recent studies. Vacuum-based deposition has also attracted...
Published: 2/13/2025   |   Inventor(s): Tianxin Li, Jian Li, Lin Song Li
Keywords(s): Fuel Cells, Energy, Materials and Electronics
Category(s): Physical Science, Manufacturing/Construction/Mechanical, Advanced Materials/Nanotechnology, Energy & Power
Method to Detect Suspicious In-Baggage Object Using Commodity WiFi
​ ​ An illustration of the system developed to use WiFi signal to detect objects of different materials. Invention Summary: To help keep consumers safe, airports and many facilities deploy different kinds of screening equipment to scan baggage and other items. Traditional in-baggage suspicious object detection involves either manual examination...
Published: 5/17/2023   |   Inventor(s): Yingying Chen, Chen Wang, Jian Liu, Hongbo Liu, Yan Wang
Keywords(s): Electronics, Sensors & Probes, Wireless
Category(s): Technology Classifications > Software & Algorithms, Technology Classifications > Software & Copyright, Technology Classifications > Physical Sciences & Engineering, Technology Classifications > Telecommunications & Networking, Technology Classifications > Artificial Intelligence & Machine Learning
Antagonists of Hyaluronan Signaling for Treatment of Airway Diseases
Airway diseases, such as Asthma and Chronic Obstructive Pulmonary Disease (COPD), constitute a major health burden worldwide. It is estimated, for example, that nearly 15.0% of the adult population in the US are affected with such diseases, and the economic cost burden is over $23 billion annually. Unfortunately, the current options for treatment of...
Published: 10/28/2024   |   Inventor(s): John Hollingsworth, Bryan Toole, Jian Liu, Stavros Garantziotis
Keywords(s): AIRWAY, ANTAGONISTS, hyaluronan, Hyperresponsiveness, IB4XXX, IBXXXX, Inflammation, IXXXXX, SIGNALING, treatment, VPXXXX, WKXXXX, YBXXXX, YCXXXX
Category(s): Collaboration Sought > Collaboration, TherapeuticArea > Ophthalmology, Application > Therapeutics, TherapeuticArea > Endocrinology, TherapeuticArea > Oncology, TherapeuticArea > Dental, Application > Diagnostics, Application > Research Materials, TherapeuticArea > Cardiology, TherapeuticArea > Infectious Disease, TherapeuticArea > Pulmonology
Self-Expanding Stent for Valve Replacement
Aortic stenosis and aortic regurgitation are the most common types of aortic valvular diseases. Such diseased aortic valves in the body are traditionally replaced with valve prosthesis by an open surgical implantation. Available for licensing and commercial development is intellectual property covering stents for use with valve prostheses. As illustrated...
Published: 10/28/2024   |   Inventor(s): Dumitru Mazilu, Ming Li, Keith Horvath
Keywords(s): AB3AXX, AB3CXX, AB3XXX, ABXXXX, Aortic Retinosis, AXXXXX, Patent Category - Mech/Elect/Soft, Self-expanding, STENT, Valve
Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing
Fabrication of metal-insulator-semiconductor photoelectrodes
Background Photoelectrochemical (PEC) water splitting is a promising technology for converting solar energy into clean and storable chemical energy. In PEC cells, semiconductors play a key role in absorbing photons from the light source to create mobile charge carriers. Various semiconductor materials have been studied for the high-performance PEC cells,...
Published: 12/11/2023   |   Inventor(s): Edward Yu, Soonil Lee, Li Ji
Keywords(s):  
Category(s): Computer > Semiconductors, Physical sciences > Energy > Renewable, green, or transitional energy
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 2/18/2025   |   Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):  
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
JobViz: User Interface for Visualization of Majors & Jobs
Invention Summary: University (and industry) career search portals and web-based job search engines allow users to search on many items (e.g., education, location, level, etc.) and then present a text based list of potential job opportunities. University career portals are not as conductive to exploration by job and career searchers as they could...
Published: 9/8/2022   |   Inventor(s): Deborah Silver, Li Liu
Keywords(s):  
Category(s): Technology Classifications > Software & Copyright, Technology Classifications > Software & Algorithms
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