Search Results - jacob+myerson

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Strategies for Mitigating Acute Side Effects of Lung-Targeted Nanocarriers
Approaches and Design Techniques to Alleviate Coagulation-Related Acute Side Effects of Lung-Targeted Nanocarriers Problem: Lipid nanoparticles (LNPs) play a crucial role in drug delivery, enabling targeted drug administration to specific tissues. LNPs tailored for lung-specific delivery often incorporate cationic (positively charged) lipids. Unfortunately,...
Published: 6/26/2024   |   Inventor(s): Jacob Brenner, Vladimir Muzykantov, Jacob Myerson, Oscar Marcos Contreras, Marco Zamora, Serena Omo-Lamai
Keywords(s): Bioengineering, Drug Delivery, Gene Editing, Gene Therapy, Nanotechnology, Platform Technology, Pulmonary
Category(s): Technology Classifications > Therapeutics
Novel Nanoparticle Composition Targeting Marginated Leukocytes
Problem: Acute inflammatory diseases, including sepsis, pneumonia, and acute respiratory distress syndrome (ARDS), account for over 1.5 million hospitalizations and 300,000 deaths per year in the US. These diseases all share a common cellular player known as marginated leukocytes. Marginated leukocytes are white blood cells that accumulate in the...
Published: 1/12/2024   |   Inventor(s): Jacob Myerson, Jacob Brenner, Vladimir Muzykantov, Landis Walsh, Priyal Patel
Keywords(s): COVID-19, Drug Delivery, Infectious Disease, Inflammation, Nanotechnology, Pulmonary
Category(s): Technology Classifications > Therapeutics