Search Results - guorong+li

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Novel Methods for Reducing Inflammation and Treating Diseases such as Parkinson's and Alzheimer's Disease

Microglia activation leads to inflammation mediated dopaminergic degeneration in the brain of patients with Parkinson and Alzheimer's Disease. Thus Identification of drugs that reduce microglia activation could prevent or reverse neuronal degeneration in these diseases and other degenerative CNS disorders. This invention describes small-peptide and...

Published: 7/25/2024 | Inventor(s): Liya Qin, Guorong Li, MIchelle Block, Wei Zhang, Po-See Chen, Giia-Shuen Peng, Jau-Shyong Hong

Keywords(s): Alzheimer disease 1, Alzheimer disease 3, Alzheimer disease 4, Alzheimer disease type 1, Alzheimer disease type 4, Alzheimer disease, familial, type 3, BBXXXX, Discovery, DOSE, femto-molar, IB3XXX, IBXXXX, Inflammation-associated, IXXXXX, Listed LPM Greene as of 4/15/2015, NB1BXX, NBXXXX, NEURODEGENERATIVE, NXXXXX, Parkinson disease 2, Parkinson disease 3, Parkinson disease 9, Parkinson disease, juvenile, autosomal recessive, Parkinson's, Patent Category - Biotechnology, Post LPM Assignment Set 20150420, Pre LPM working set 20150418, Prevention, therapeutic, therapeutics, Ultra-low, VEXXXX, WJXXXX, WKXXXX, YAXXXX, YBXXXX, YCXXXX

Category(s): Collaboration Sought > Collaboration, Application > Therapeutics, TherapeuticArea > Neurology, TherapeuticArea > Immunology, Application > Diagnostics, Application > Research Materials

Transgenic T cells with enhanced anti-tumor cytotoxicity to treat cancers

CAR T cell therapy recently achieved success in treating blood cancers. Drugs Kymriah and Yescarta are FDA approved for treating hematological malignancies. However, existing T cell therapies are not effective in treating solid tumors, partly due to T cell exhaustion and lack of sufficient memory T cell populations. GW researchers invented a way...

Published: 7/30/2024 | Inventor(s): Rong Li, Bogang Wu

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Category(s): Technology Classifications > Therapeutics > Cells

Amphiphilic macromolecules with novel hydrophobic segments

Invention Summary: Cardiovascular diseases are the leading cause of mortality in developed countries. Atherosclerosis, defined as the buildup of lipid rich plaques within the vascular intima, is the foremost pathology underlying these conditions. This causes irregular uptake of oxidized low-density lipoproteins (OxLDL) which leads...

Published: 4/17/2024 | Inventor(s): Kathryn Uhrich, Allison Faig, Dalia Abdelhamid, Li Gu

Keywords(s): Antibacterial, Biomaterials, Polymers & Composites

Category(s): Technology Classifications > Healthcare & Life Sciences, Technology Classifications > Therapeutics

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...

Published: 7/30/2024 | Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li

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Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment

Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers

Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li, Jacques Albert

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources

All-Fiber Multicore Fiber Laser Devices

Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...

Published: 4/3/2023 | Inventor(s): Nasser Peyghambarian, Axel Schülzgen, Li Li

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Category(s): Technology Classifications > Imaging & Optics, Technology Classifications > Imaging & Optics > Fiber Optics, Technology Classifications > Imaging & Optics > Lasers & Other Sources