Search Results - eric+j.+sorscher

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CFTR Modulators for Treating Rare Forms of Cystic Fibrosis
Application Small molecules to treat cystic fibrosis and other pulmonary diseases. Key Benefits Rescue rare variants of CFTR gene. Serve as PDE4 inhibitors with strong anti-inflammatory effects. Market Summary Cystic fibrosis (CF) is a progressive, genetic disorder that arises from mutations in the cystic fibrosis transmembrane conductance...
Published: 8/22/2024   |   Inventor(s): Eric J. Sorscher, Jeong Hong, Haian Fu, Yuhong Du, Huw Davies, Andras Rab, Candela Manfredi, Xun Yang, Zhi Ren
Keywords(s): Rare/Orphan Diseases, Respiratory, Small Molecule
Category(s): TechPub Algolia > Therapeutics
PNP-based Solid Tumor Therapy in Conjunction with Checkpoint Blockade Inhibitors
Application Treatment of solid tumors combining purine nucleoside phosphorylase (PNP) technology with checkpoint blockade inhibition. Key Benefits Safe and effective method for markedly enhancing checkpoint blockade therapy for refractory tumors. Checkpoint inhibitor therapy is FDA-approved and already in use. Market Summary Checkpoint blockade...
Published: 7/30/2024   |   Inventor(s): Eric J. Sorscher, Turang Behbahani, Regina Rab, Annette Ehrhardt, Jeong Hong, Disha Joshi
Keywords(s): Cell/Gene Therapy, Immunology/Inflammation, Oncology
Category(s): TechPub Algolia > Therapeutics