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Search Results - elizabeth+sweeney
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Engineered Nanoparticles Improve Immune Response to Photothermal Therapy for Cancer
Neuroblastoma is a severe form of cancer and accounts for 15% of all cancer related deaths among children. However, the current modalities of treating this cancer have limited efficacy and are deficient in preventing recurrence. This can be attributed to the heterogeneous and immunosuppressive nature of the cancer coupled with low neoantigen expression. Researchers...
Published: 7/30/2024
|
Inventor(s):
Rohan Fernandes
,
Elizabeth Sweeney
,
Juliana Cano-Mejia
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Nanoparticles
T cells targeted against multiple antigens for cancer treatment
GW researchers developed a cell therapy platform to manufacture multi-antigen-specific immune cell products for treating cancer. Tumors often are sheltered from attack by a patient's immune system. One problem is immune cells at the tumor may be dysfunctional, so they are unable to recognize and eliminate the tumor cells. Current gold-standard...
Published: 7/30/2024
|
Inventor(s):
Elizabeth Sweeney
,
Rohan Fernandes
,
Conrad Cruz
,
Palak Sekhri
,
Preethi Balakrishnan
,
Matthew Tovar
Keywords(s):
Category(s):
Technology Classifications > Therapeutics > Cells
Novel Codon-Optimized MUT Gene Therapeutic for Methylmalonic Acidemia (MMA)
Methylmalonic Acidemia (MMA) is a metabolic disorder characterized by increased acidity in the blood and tissues due to toxic accumulation of protein and fat by-products resulting in seizures, strokes, and chronic kidney failure. A significant portion of MMA cases stem from a deficiency in a key mitochondrial enzyme, methylmalonyl-CoA mutase (MUT),...
Published: 10/28/2024
|
Inventor(s):
Colin Shea
,
Ciprian Crainiceanu
,
Elizabeth Sweeney
,
Russell Shinohara
,
Arthur Goldsmith
,
Daniel Reich
Keywords(s):
Automatic
,
brain
,
Detection
,
IMAGING
,
Incidence
,
Lesion
,
Listed LPM Shmilovich as of 4/15/2015
,
Longitudinal
,
Magnetic
,
MULTIMODALITY
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
Resonance
,
software
,
SuBLIME:
,
VPXXXX
,
WJXXXX
,
XEXXXX
Category(s):
TherapeuticArea > Cardiology
,
TherapeuticArea > Oncology
,
TherapeuticArea > Ophthalmology
,
Application > Therapeutics
,
TherapeuticArea > Endocrinology
,
TherapeuticArea > Dental
,
TherapeuticArea > Infectious Disease
OASIS: Automated brain lesion detection using cross-sectional multimodal magnetic resonance imaging
This invention is a novel statistical method for automatically detecting lesions in cross-sectional brain magnetic resonance imaging (MRI) studies. OASIS uses multimodal MRI from one image acquisition session and produces voxel-level probability maps of the brain that quantifies the likelihood that each voxel is part of a lesion. Binary lesion segmentations...
Published: 10/28/2024
|
Inventor(s):
Ciprian Crainiceanu
,
Elizabeth Sweeney
,
Russell Shinohara
,
Arthur Goldsmith
,
Navid Shiee
,
Dzung Pham
,
Daniel Reich
Keywords(s):
Automated
,
brain
,
CNRM CRADA
,
Cross
,
Detection
,
IMAGING
,
Lesion
,
Listed LPM Shmilovich as of 4/15/2015
,
Magnetic
,
MULTIMODALITY
,
OASIS:
,
Post LPM Assignment Set 20150420
,
Pre LPM working set 20150418
,
Resonance
,
SECTIONAL
,
software
,
VEXXXX
,
WBXXXX
,
WIXXXX
,
XFXXXX
Category(s):
Collaboration Sought > Licensing
,
Application > Medical Devices
,
Application > Research Materials
,
Application > Software / Apps
,
Application > Diagnostics
,
Application > Non-Medical Devices
,
TherapeuticArea > Neurology
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 7/30/2024
|
Inventor(s):
Payman Dehghanian
,
Shiyuan Wang
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
Distributed Feedback Fiber Laser Pumped by Multimode Diode Lasers
Researchers at the University of Arizona College of Optical Sciences and Canada's Carleton University recently succeeded in fabricating high reflectivity (>99%) Fiber Bragg Gratings (FBGs) into phosphate glass fibers using UV light and a phase mask technique. With this new manufacturing technique, fiber lasers can be created as single monolithic...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
,
Jacques Albert
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources
All-Fiber Multicore Fiber Laser Devices
Researchers at the University of Arizona have developed a compact, power-scalable, alignment-free fiber laser that takes a new approach to stabilizing phase-locked operation of multi-core fiber lasers by completely removing all free space optical components. This high-brightness, all-fiber laser package uses passive optical fiber spliced at both ends...
Published: 4/3/2023
|
Inventor(s):
Nasser Peyghambarian
,
Axel Schülzgen
,
Li Li
Keywords(s):
Category(s):
Technology Classifications > Imaging & Optics
,
Technology Classifications > Imaging & Optics > Fiber Optics
,
Technology Classifications > Imaging & Optics > Lasers & Other Sources