Search Results - chenjie+lin

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Transgenic Mouse Model for Marfan Syndrome Research

Description: A genetically modified mouse model carrying the FBN1Q2469X mutation enables advanced study of systemic Marfan Syndrome manifestations and therapeutic development. This innovative transgenic mouse model incorporates a mutation analogous to the human FBN1Q2467X gene mutation linked to Marfan Syndrome, resulting in fibrillin-1 deficiency...

Published: 12/23/2025 | Inventor(s): Li Li, Shichao Wu, Jiawei Zhao

Keywords(s):

Category(s): Technology Category > Research tools, Technology Category > Animal models, Technology Category > Biology, Technology Category > Diagnostic

Hyperbranched Polyglycerol Encapsulated Proteins for Oral Protein Delivery (Case No. 2012-425)

Patent Abstract: Methods for modifying therapeutic agents such as therapeutic biomolecules, such as proteins for improved oral, rectal or transmucosal delivery, as well as compositions made using such methods and methods of administering such compositions to a subject, are disclosed. Specifically, the therapeutic agents are conjugated to hyperbranched...

Published: 12/1/2025 | Inventor(s): Yunfeng Lu, Juanjuan Du, Jie Li, Yang Liu

Keywords(s):

Category(s): Platforms > Drug Delivery

Ultrafast Thin-Film Vapor Deposition Technique

Invention Description The demand for advanced thin-film deposition techniques has grown substantially in recent years, driven by the development of next-generation electronic, optoelectronic, and energy devices. Traditional deposition methods, such as chemical vapor deposition, molecular beam epitaxy, and physical vapor deposition, have well-established...

Published: 2/26/2026 | Inventor(s): Feng Yan, Lin Li

Keywords(s):

Category(s): Semiconductors, Materials & Processes, Microelectronics, Physical Science, Semiconductor Devices, Manufacturing/Construction/Mechanical

Novel treatment for pseudomyxoma peritonei

Reference #: 1692 The University of South Carolina is offering licensing opportunities for Novel treatment for pseudomyxoma peritonei. Background: Pseudomyxoma peritonei (PMP) is a rare cancer, which originates as an appendiceal neoplasm. Due to its usually poor vascularization and floating as nodules, PMP spreads easily to the peritoneal cavity,...

Published: 1/28/2026 | Inventor(s): Jie Li, Daping Fan, Hexin Chen, Traci Testerman

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application

Reference #: 1678 The University of South Carolina is offering licensing opportunities for Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application. Background: The gut microbiota plays a key role in health and disease. The balance between beneficial genera (such as Alistipes and Odoribacter) and harmful species (such...

Published: 2/9/2026 | Inventor(s): Jie Li, Hexin Chen, Daping Fan

Keywords(s):

Category(s): Biomedical and Life Sciences, Health Sciences

Fabrication of metal-insulator-semiconductor photoelectrodes

Background Photoelectrochemical (PEC) water splitting is a promising technology for converting solar energy into clean and storable chemical energy. In PEC cells, semiconductors play a key role in absorbing photons from the light source to create mobile charge carriers. Various semiconductor materials have been studied for the high-performance PEC cells,...

Published: 1/13/2026 | Inventor(s): Edward Yu, Soonil Lee, Li Ji

Keywords(s):

Category(s): Computer > Semiconductors, Physical sciences > Energy > Renewable, green, or transitional energy

Novel Multi-Omics Aging Clock

A multi-omics clock analyzes multiple layers of omics data with machine learning to predict remaining lifespan of mammals, particularly for animal model studies. Large omics data sets may be used from combinations of genomics, proteomics, lipids, etc. available from blood or other simple sample collection. This tool can robustly capture changes...

Published: 3/12/2024 | Inventor(s): George Sutphin, Samuel Freitas, Megha Padi, Chen Chen

Keywords(s):

Category(s): Technology Classifications > Life Sciences > Biomarkers, Technology Classifications > Research Tools > Animal Models, Technology Classifications > Research Tools > Screening assays, Technology Classifications > Research Tools > Simulators and Modeling Tools

Autonomous Drone for railroad track inspection

Reference #: 01564 The University of South Carolina is offering licensing opportunities for Autonomous Drone for railroad track inspection Background: The current practices suffer from three main drawbacks: 1) Human pilot cost is significant. The schedule of the drone-based track inspection is contingent on the pilot’s availability rather than...

Published: 12/3/2025 | Inventor(s): Yu Qian, Yi Wang, Chen Chen

Keywords(s): autonomous drone, flight control, image processing, railroad track inspection, self-navigation

Category(s): Engineering and Physical Sciences

Scalable two-phase cooling plates

Reference #: 01575 The University of South Carolina is offering licensing opportunities for Scalable two-phase cooling plates Background: Two-phase cooling usually fails at relatively low heat loads due to the loss of liquid supply. For real applications, two-phase cooling technologies need to match the size of electronic components. However, the...

Published: 2/11/2026 | Inventor(s): Chen Li, Wei Chang, Enrico Santi, Bo Tian

Keywords(s): cold plate, high power device, Thermal management, Two-phase cooling

Category(s): Engineering and Physical Sciences, Software and Computing

Non-Invasive Plasma Discharge Tube Device for Treating Brain Tumors

Treating brain tumors, like glioblastoma, is challenging. Current glioblastoma drugs, Rapamycin and Temozolomide (TMZ), generally only extend life for a matter of months, are not very effective in treating recurring tumors, and have significant clinical toxicity. A novel Plasma Discharge Tube (PDT) device has the potential to be more effective and less...

Published: 1/9/2026 | Inventor(s): Michael Keidar, Li Lin, Vikas Soni, Xiaoliang Yao, Dayun Yan, Jonathan Sherman

Keywords(s):

Category(s): Technology Classifications > Medical Devices, Technology Classifications > Medical Devices > Surgical

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