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Liquid Biopsy Detection of TF-Ag-α-Positive Cancer-Associated Exosomes
A liquid biopsy assay detecting TF-Ag-α–positive tumor-derived exosomes for cancer screening, early detection and treatment monitoring. Background: Cancer diagnostics are rapidly evolving as early detection and treatment monitoring are critical to improving patient outcomes. Traditional methods such as imaging and tissue biopsies...
Published: 7/29/2026   |   Updated: 7/28/2026   |   Inventor(s): Yun Wu, Grace Dy, Kate Rittenhouse-Olson
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Diagnostics, Technology Classifications > Engineering, Technology Classifications > Medical Devices, Technology Classifications > Sensors
Low-Cost Mechanically Robust Silica Aerogel Technology
A low-cost mechanically robust silica aerogel technology enhances fiber-based building insulation R-value performance, soundproofing, thermal barrier textiles fabrics, ceramic foams, papers and composites thereof. Background: Energy efficiency in buildings, aerospace, extreme environments and many other sectors seek low cost, scalable, lightweight...
Published: 7/24/2026   |   Updated: 7/24/2026   |   Inventor(s): Shenqiang Ren, Lu An
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Energy Conservation, Technology Classifications > Materials and Chemicals, Technology Classifications > Nanotechnology
Novel Antifungal Agents with Dual Mechanism of Action
With a clear and growing unmet need, a novel mechanism of action, and demonstrated in vitro superiority over current standard-of-care agents, these novel boron-based antifungal agents represent a compelling early-stage opportunity with significant commercial and public health relevance. Background: Invasive fungal infections caused by opportunistic...
Published: 7/24/2026   |   Updated: 7/24/2026   |   Inventor(s): Bhaskar Das, Joshua Nosanchuk, Daniel Miranda
Keywords(s): Chemistry, Featured, Healthcare, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
mmHeat: Autonomous Millimeter-Wave Robotic System for Non-Contact 3D Thermal Conductivity Mapping of Building Envelopes
An autonomous robotic inspection system that uses millimeter wave radar to generate non contact, volumetric 3D thermal conductivity maps of opaque building materials. BACKGROUND: Buildings lose approximately 25 to 30% of heating and cooling energy through hidden envelope defects such as moisture infiltration, insulation voids, and thermal bridges....
Published: 7/22/2026   |   Updated: 7/22/2026   |   Inventor(s): Xiaoyu Zhang, Wenyao Xu, Chi Zhou, Wei Bo
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Materials and Chemicals, Technology Classifications > Sensors
Tools to Predict Clinical Immunogenicity
In vitro tools for predicting clinical immunogenicity of subcutaneously administered antigens, whether for therapeutic or prophylactic applications. Background: Immunogenicity, the propensity of a product to elicit an immune response to itself or related structures, may be desirable (e.g. vaccine candidates) or undesirable...
Published: 7/24/2026   |   Updated: 7/9/2026   |   Inventor(s): Sathy Balu-Iyer, Aditi Venkatesh
Keywords(s): Featured, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Research Tools and Reagents, Technology Classifications > Screens and Assays
Novel Small Molecule Anabolic Agents for Osteoporosis
-Analogs of a naturally occurring phytoestrogen that hold promise for the treatment of osteoporosis and other conditions impacting peri- and post-menopausal women. Background: Menopause significantly speeds bone loss and increases the risk of osteoporosis, a condition characterized by decreased bone mineral density and which impacts more than 200M...
Published: 7/24/2026   |   Updated: 7/7/2026   |   Inventor(s): Bhaskar Das, Hiranmoy Das
Keywords(s): Featured, Pharmaceutical, Research Tool, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
Novel Small Molecule Agents for Glioblastoma
Brain-penetrant small molecule agents possessing a dual targeting mechanism of action (LonP1 and CT-L proteasome inhibition) that may overcome resistance mechanisms that currently plague standard of care treatments for brain tumors such as glioblastoma. Background: Malignant astrocytomas, including glioblastoma (GBM), represent highly aggressive intracranial...
Published: 7/10/2026   |   Updated: 7/6/2026   |   Inventor(s): Bhaskar Das, Daniela Bota
Keywords(s): Chemistry, Nanotechnology, Pharmaceutical, Research Tool, Screening, Technologies, Therapeutic and Vaccines
Category(s): Campus > University at Buffalo, Technology Classifications > Drug Design and Synthesis, Technology Classifications > Therapeutics and Vaccines
Methods for Low-Overhead, Fault-Tolerant CNOT Operations.
Methods for Low-Overhead, Fault-Tolerant CNOT Operations between two Non-Nearest Neighboring Logical Qubits Background: The term Noisy Intermediate-Scale Quantum (NISQ) has been used to describe the current state of quantum computing technology because (1) qubits are highly error prone; and (2) the number of qubits in a single (monolithic) Quantum...
Published: 6/29/2026   |   Updated: 6/29/2026   |   Inventor(s): Chunming Qiao, Sean Grzenda
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Computers, Technology Classifications > Quantum Computing
Flexible Nanophotonic Cavity-Enhanced Infrared Photodetectors Employing Double Quantum Wells
Double-quantum-well infrared photodetectors (DQWIPs) integrated with nanophotonic cavities enable highly responsive mid-infrared detection through enhanced intersubband absorption in the thin semiconductor heterostructure. Additionally, the technology is compatible with flexible substrates. Background: Quantum Well Infrared Photodetectors (QWIPs)...
Published: 6/25/2026   |   Updated: 6/15/2026   |   Inventor(s): Peter Liu, Puspita Paul
Keywords(s): Imaging: Medical Imaging, Instrumentation, Night vision and thermal imaging, Optics, Research Tool, Sensors, Surveillance, Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Electronics, Technology Classifications > Engineering, Technology Classifications > Semiconductor Devices and Manufacturing, Technology Classifications > Quantum Computing
Reduction of Lipid Accumulation Reverses Aging
Therapeutic strategy to treat age-related cardiovascular disease and restore cardiovascular function through maintenance of lipid homeostasis. Background: Age is a key risk factor for cardiovascular disease such as atherosclerosis, which is characterized by endothelial dysfunction, extracellular matrix remodeling, lipid accumulation, chronic inflammation...
Published: 6/19/2026   |   Updated: 6/15/2026   |   Inventor(s): Stylianos Andreadis, Yulun Wu, Pihu Mehrotra
Keywords(s): Technologies
Category(s): Campus > University at Buffalo, Technology Classifications > Biological Materials, Technology Classifications > Healthcare, Technology Classifications > Biomedical Science and Engineering, Technology Classifications > Therapeutics and Vaccines
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