Search Results - kirstie+swingle

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CRISPR-Cas/Transcription Factor-Based Assay for Detection of Molecular Analytes
The ability to detect small molecules and other chemical analytes is important for many applications from assessing drinking water to monitoring effluents and ensuring food and drinks are safe to consume. While synthetic biology has enabled the development of molecular biosensors, such as transcription factors, to detect small molecules, they rely on...
Published: 10/26/2023   |   Inventor(s): Alexander Green, Soma Chaudhary, Kirstie Swingle
Keywords(s):  
Category(s): Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Life Science (All LS Techs), Medical Diagnostics/Sensors
Utilization of CRISPR-Cas Systems for Analyte Detection
Compared to nucleic acid tests, current immunoassays suffer from low specificity and poor sensitivity. Attempts have been made to combine protein detection with nucleic acid amplification schemes to increase sensitivity, however, these techniques require multiple processing steps and are limited to fluorescent readout or the use of thermal cycling,...
Published: 2/23/2023   |   Inventor(s): Alexander Green, Kirstie Swingle
Keywords(s):  
Category(s): Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Chemical/Biological Sensors, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Medical Diagnostics/Sensors, Proteomic Assays/Reagents/Tools, Intelligence & Security
Pathogen Molecular Detection Platform
Accurate detection and diagnosis of infectious diseases is paramount to appropriate treatment and better outcomes. Despite tremendous efforts to advance new diagnostic techniques, there are still critical gaps in the healthcare system in quickly diagnosing and responding to infectious diseases. Current diagnostic technologies identify pathogens by detecting...
Published: 2/23/2023   |   Inventor(s): Alexander Green, Matthew Gilliam, Kirstie Swingle, Nicholas Stephanopoulos, Neal Woodbury
Keywords(s):  
Category(s): Advanced Materials/Nanotechnology, Applied Technologies, Bioanalytical Assays, Chemistries & Devices, Diagnostic Assays/Devices, Genomic Assays/Reagents/Tools, Life Science (All LS Techs), Proteomic Assays/Reagents/Tools, Medical Diagnostics/Sensors