Search Results - yusuf+hannun

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Enzyme Replacement Therapy in Niemann-Pick Disease
The inventors have developed an aSMaseKO mouse model that can be utilized as a proof-of-concept for using the mutant enzyme in enzyme replacement studies in patients with Niemann-Pick disease (NPD). NPD is a rare, inherited disease that affects the body's ability to metabolize fat (cholesterol and lipids) within cells. The inventors suggest that...
Published: 8/14/2025   |   Inventor(s): Ashley Snider, Yusuf Hannun, Russel Jenkins, Benjamin Newcomb
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics
Cost-Effective Single-Step Process for the Catalytic Conversion of Methane to Methanol/Formaldehyde
Unmet Need: Currently there is no technology available in the market capable of producing Dimethyl Ether (DME) from methane in a single reactor. DME is an attractive substitute for diesel due to its high cetane number, which is a measure of its ignitibility in compression ignition engines. In addition, DME’s quiet combustion and inability to form...
Published: 10/8/2024   |   Inventor(s): Su Ha, M Norton, Oscar Marin Flores
Keywords(s):  
Category(s): Technologies > Health & Well-being > Chemistry, Technologies > Energy & Environment > Energy
Chance-Constrained Optimization for Treatment of Prostate and Other Cancers in Intensity-Modulated Proton Therapy
The quality of IMPT treatment plans may be drastically diminished by uncertainties such as proton range and patient setup errors. If these uncertainties are not figured into treatment planning, the dose distribution that the patient receives may not be the same as the planned dose distribution. New treatment plans, which include optimized software/programming,...
Published: 7/4/2025   |   Inventor(s): Jianming Liang, Yu An, Wei Liu
Keywords(s):  
Category(s): Computing & Information Technology, Life Science (All LS Techs), Medical Imaging