Search Results - ashley+snider

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Secretory Acid Sphingomyelinase Activity as a Diagnostic Marker in Colorectal Cancer
This invention utilizes the activity of secretory acid sphingomyelinase (S-SMase) in patient serum as a biomarker for the early or enhanced detection of colorectal neoplasia, including colorectal cancer (CRC). Background: Colorectal cancer (CRC) is one of the most common cancers worldwide, ranking third in incidence and second in cancer-related deaths...
Published: 9/22/2025   |   Inventor(s): Ashley Snider, Nathan Ellis, Justin Snider, Peter Lance
Keywords(s):  
Category(s): Technology Classifications > Healthcare Portfolios > Oncology, Technology Classifications > Life Sciences > Diagnostics
Enzyme Replacement Therapy in Niemann-Pick Disease
University of Arizona researchers have developed an acid sphingomyelinas knockout (aSMaseKO) mouse model as a proof-of-concept for using the mutant enzyme in enzyme replacement studies for Niemann-Pick disease (NPD). NPD is a rare, inherited disease that affects the body's ability to metabolize fat within cells. The inventors suggest that a mutant...
Published: 10/26/2025   |   Inventor(s): Ashley Snider, Yusuf Hannun, Russel Jenkins, Benjamin Newcomb
Keywords(s):  
Category(s): Technology Classifications > Life Sciences > Therapeutics