Search Results - yeon+sun+lee

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Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit Endospores
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit EndosporesResearchers at Augusta University have invented skin-friendly compositions and methods for killing, inactivating, or otherwise reducing the bacterial endospores by using an effective amount of the green tea EGCG or its derivatives. EGCG research shows clear application for a hand sanitizer...
Published: 4/21/2023   |   Inventor(s): Stephen Hsu, Lee Lee, Tin-Chun Chu
Keywords(s):  
Category(s): Therapeutics
Novel Amphipathic Ligands for the Dynorphin Binding Site on the Bradykinin Receptor
The core portion of the dynorphin protein was identified and modifications were made to that core to allow dynorphin to interact and antagonize a bradykinin receptor which is partially responsible for pain sensations. Applications: Since the invention antagonizes a receptor partly responsible for pain, the modified protein can be used as a form...
Published: 4/3/2023   |   Inventor(s): Yeon Sun Lee
Keywords(s): ongoing pain
Category(s): Technology Classifications > Life Sciences > Biologics
Discovery of Novel Amphipathic Ligands for the Dynorphin Binding Site on the Bradykinin Receptor
This invention is a dynorphin analog designed to interact with a receptor that is partly responsible for pain sensations. Dynorphin analog targets the bradykinin receptors instead of the f NMDA receptors. The ligands are novel in the deletion of an arginine residue in position 7 which has been recognized as an essential residue for opioid and non-opioid...
Published: 4/3/2023   |   Inventor(s): Yeon Sun Lee, Victor Hruby, Josephine Lai, Frank Porreca
Keywords(s): [des-Arg7]-dynorphin analogs, amphipathic bradykinin receptor, non-opioid effect of dynorphin, pain, pharmacophore
Category(s): Technology Classifications > Life Sciences, Technology Classifications > Life Sciences > Small Molecules