Inteum Company
Links
seedsprint
Visible Legacy
RSS
News & Resources
Inteum Company News
Inteum Library
Subscribe
Search Results - yeon+sun+lee
5
Results
Sort By:
Published Date
Updated Date
Title
ID
Descending
Ascending
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit Endospores
Modified Green Tea Polyphenol EGCG and EGCG-ester Inhibit EndosporesResearchers at Augusta University have invented skin-friendly compositions and methods for killing, inactivating, or otherwise reducing the bacterial endospores by using an effective amount of the green tea EGCG or its derivatives. EGCG research shows clear application for a hand sanitizer...
Published: 4/21/2023
|
Inventor(s):
Stephen Hsu
,
Lee Lee
,
Tin-Chun Chu
Keywords(s):
Category(s):
Therapeutics
Novel Amphipathic Ligands for the Dynorphin Binding Site on the Bradykinin Receptor
The core portion of the dynorphin protein was identified and modifications were made to that core to allow dynorphin to interact and antagonize a bradykinin receptor which is partially responsible for pain sensations. Applications: Since the invention antagonizes a receptor partly responsible for pain, the modified protein can be used as a form...
Published: 4/3/2023
|
Inventor(s):
Yeon Sun Lee
Keywords(s):
ongoing pain
Category(s):
Technology Classifications > Life Sciences > Biologics
Mixed MOR/DOR Agonist Activity Provides Improved Analgesic Efficacy and Tolerability for the Treatment of Pathological Pain States Including Pain-Induced Adaptive Changes in the Nervous System
This invention is the discovery of lead ligands, LYS739 and LYS744, for the treatment of chronic pain including neuropathic pain. These are single compounds representing a novel therapeutic pathway to improve analgesic efficacy. Background: Chronic pain is poorly managed with current medications because long term administration or higher doses may...
Published: 4/3/2023
|
Inventor(s):
Yeon Sun Lee
,
Victor Hruby
,
Frank Porreca
Keywords(s):
Category(s):
Technology Classifications > Life Sciences
,
Technology Classifications > Healthcare Portfolios > Neurology
Discovery of a Tetra Peptide with Dual Mu/Delta Opioid Receptor Agonist and Kappa Opioid Receptor Antagonist Properties for the Treatment of Chronic Pain
This invention relates to ligands for mu, delta, and kappa opioid receptors, more particularly to ligands that are agonists for mu and delta opioid receptors, and in some cases ligands that are also antagonists for kappa opioid receptors. Background: Opioids are commonly used in the treatment of severe pain. Opioids have analgesic activity through...
Published: 4/3/2023
|
Inventor(s):
Yeon Sun Lee
,
Victor Hruby
,
Frank Porreca
Keywords(s):
Category(s):
Technology Classifications > Life Sciences > Therapeutics
Discovery of Novel Amphipathic Ligands for the Dynorphin Binding Site on the Bradykinin Receptor
This invention is a dynorphin analog designed to interact with a receptor that is partly responsible for pain sensations. Dynorphin analog targets the bradykinin receptors instead of the f NMDA receptors. The ligands are novel in the deletion of an arginine residue in position 7 which has been recognized as an essential residue for opioid and non-opioid...
Published: 4/3/2023
|
Inventor(s):
Yeon Sun Lee
,
Victor Hruby
,
Josephine Lai
,
Frank Porreca
Keywords(s):
[des-Arg7]-dynorphin analogs
,
amphipathic bradykinin receptor
,
non-opioid effect of dynorphin
,
pain
,
pharmacophore
Category(s):
Technology Classifications > Life Sciences
,
Technology Classifications > Life Sciences > Small Molecules