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Search Results - xiaolu+(lulu)+cambronne
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Genetically encoded protein-based fluorescent biosensor for adenosine diphosphate ribose
Background Adenosine diphosphate ribose (ADPR) is a biologically important molecule that is known to regulate oxidative stress, calcium homeostasis, and mitochondrial function. Very little is known about ADPR signaling because it is a fast and transient process. Our innovation addresses this challenge by streamlining the development of fluorescent...
Published: 6/26/2024
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Inventor(s):
Xiaolu Cambronne
,
Shivansh Goyal
Keywords(s):
Category(s):
Life sciences > Therapeutics > Synthetic biology
,
Life sciences > Research tools > Tool/assay/screening platform
y-AApeptide-based long-acting pan-coronavirus fusion inhibitor with dual targets in spike protein and oral bioavailability
Advantages: S-20-1 demonstrates potent inhibitory action, this broad-spectrum activity suggests that S-20-1 could be effective against a wide range of coronaviruses, making it a valuable candidate for pandemic preparedness and management. The research provides insights into the mechanism of action of S-20-1, demonstrating its ability to bind...
Published: 9/25/2023
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Inventor(s):
Jianfeng Cai
,
Shibo JIANG
,
Lu LU
,
Songyi XUE
,
Xinling WANG
,
Lei WANG
,
Wei XU
,
Shuai XIA
Keywords(s):
Drug Discovery
,
Immunology
Category(s):
Technology Classifications > Medical > Biotechnology
Network-Coded Multiple Access
[Licensing negotiation in progress] [Invitation for Expression of Interest - Deadline: 16 June 2016] Systems and methods include a first wireless local area network (WLAN) system that jointly exploit physical-layer network coding (PNC) and multi-user decoding (MUD) to boost system throughput. This multiple access mode is referred to as Network-Coded...
Published: 1/29/2024
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Inventor(s):
Soung Chang Liew
,
Lu LU
,
Lizhao You
Keywords(s):
Network Coding
,
Wireless Local Area Network
Category(s):
Information and Communications Technology
Novel biosensor for direct measurement of bioavailable NAD+
Summary This technology provides a unique cell-based platform for targeting NAD+-(nicotinamide adenine dinucleotide) regulatory pathways in the treatment of human diseases. An emerging theme in age-related pathologies—e.g. neurodegeneration, cancer, cardiovascular disease, inflammation, type 2 diabetes, and metabolic disease—is due to the...
Published: 9/23/2022
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Inventor(s):
Richard Goodman
,
Michael Cohen
,
Xiaolu (Lulu) Cambronne
,
Melissa Stewart
Keywords(s):
Research Tools - Screening
Category(s):
Research Tools