Search Results - xiaodong+(michael)+xu

3 Results

Sort By:

Human and Improved Murine Monoclonal Antibodies Against CD22

Abstract: CD22 is a common cell surface glycoprotein expressed in B-cells and present in B-cell lymphomas; e.g., hairy cell leukemia (HCL), non-Hodgkins lymphoma (NHL), chronic lymphoblastic leukemia (CLL), and other cancers. It is therefore a target for cancer immunotherapy. Conjugation of anti-CD22 monoclonal antibodies with toxins or drugs has shown...

Published: 8/14/2024 | Inventor(s): Dimiter Dimitrov, Xiaodong Xiao, Ira Pastan

Keywords(s): antibodies, ANTIGEN, B-CELL, B-Cell Lymphoma, Bcl, CANCER, CD22, Chronic Lymphoblastic Leukemia, CLL, Dimitrov, Hairy cell leukemia, HCL, Human, monoclonal, NHL, non-Hodgkins lymphoma, Oncology

Category(s): Collaboration Sought > Collaboration, Collaboration Sought > Licensing, TherapeuticArea > Oncology, Application > Therapeutics

Novel Inhibitors of Secretion of Hepatitis B Virus Antigens

PAGE TITLE Novel Inhibitors of Secretion of Hepatitis B Virus Antigens PAGE SUMMARY More than 350 million people globally are infected with chronic hepatitis B virus (HBV), and the virus causes up to 1 million deaths per year, including from complications of hepatocellular carcinoma or cirrhosis. While there are some small molecule therapeutics...

Published: 7/23/2024 | Inventor(s): Timothy Block, Xiaodong (michael) Xu, Andrea (andy) Cuconati, Tong (tony) Xiao

Keywords(s):

Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Hepatic

Functionalized Benzene Sulfonamides that inhibit Hepatitis B Virus Covalently Closed Circular DNA formation and their method of use.

PAGE TITLE Functionalized benzene sulfonamides as therapeutics for hepatitis B virus PAGE SUMMARY More than 350 million people globally are infected with chronic hepatitis B virus (HBV), and the virus causes up to 1 million deaths per year, including from complications of hepatocellular carcinoma or cirrhosis. While there are some small molecule...

Published: 7/23/2024 | Inventor(s): Timothy Block, Ju-Tao Guo, Haitao Guo, Andrea (andy) Cuconati, Xiaodong (michael) Xu, Huagang Lu, Dawei Cai

Keywords(s):

Category(s): Pharmaceuticals & Therapeutics, Pharmaceuticals & Therapeutics > Pharma: Hepatic