Search Results - inflammation+and+autoimmunity

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Treatment of pulmonary hypertension
Pulmonary hypertension (PH) is a devastating disease associated with progressive low blood oxygen levels, heart failure, and a mortality rate of 50% within three years of diagnosis. PH can occur in association with chronic lung disorders including Interstitial Lung Disease (ILD), Chronic Obstructive Pulmonary Disease (COPD) and scleroderma.Hypoxia...
Published: 9/25/2023   |   Inventor(s): Edmund Miller
Keywords(s):  
Category(s): Inflammation and Autoimmunity
Peptide mimics of melanocyte stimulating hormone
The human gut naturally contains a large mass of microorganisms that collectively perform critical functions, such as degradation of otherwise indigestible components of our diet. The mechanisms that suppress host inflammatory responses to these living cultures within our GI tract are not well understood – the presence of minute amounts of the...
Published: 3/23/2021   |   Inventor(s): Jesse Roth
Keywords(s): Inflammatory disease
Category(s): Inflammation and Autoimmunity
Antileukinates in the prevention of transplant rejection
Alpha-chemokines play important roles in both inflammation and tumor development. They bind to specific surface receptors to induce leukocyte migration and activation, angiogenesis, and to stimulate tumor growth. Dr. Miller developed a peptide inhibitor of the α-chemokine receptors, CXCR1 and CXCR2, and went on to show that this inhibitor (dubbed...
Published: 4/26/2016   |   Inventor(s): Edmund Miller, Shin Hirayama, Takeshi Shiraishi
Keywords(s): Transplant rejection
Category(s): Inflammation and Autoimmunity